Cargando…

Affibody-mediated PET imaging of HER3 expression in malignant tumours

Human epidermal growth factor receptor 3 (HER3) is involved in the progression of various cancers and in resistance to therapies targeting the HER family. In vivo imaging of HER3 expression would enable patient stratification for anti-HER3 immunotherapy. Key challenges with HER3-targeting are the re...

Descripción completa

Detalles Bibliográficos
Autores principales: Rosestedt, Maria, Andersson, Ken G., Mitran, Bogdan, Tolmachev, Vladimir, Löfblom, John, Orlova, Anna, Ståhl, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4609989/
https://www.ncbi.nlm.nih.gov/pubmed/26477646
http://dx.doi.org/10.1038/srep15226