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Factors Associated with Medication Nonadherence among Hypertensives in Ghana and Nigeria

Background. Blood pressure (BP) control is poor among hypertensives in many parts of sub-Saharan Africa. A potentially modifiable factor for control of BP is medication nonadherence (MNA); our study therefore aimed to determine factors associated with MNA among hypertensives in Ghana and Nigeria. Me...

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Autores principales: Boima, Vincent, Ademola, Adebowale Dele, Odusola, Aina Olufemi, Agyekum, Francis, Nwafor, Chibuike Eze, Cole, Helen, Salako, Babatunde L., Ogedegbe, Gbenga, Tayo, Bamidele O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4610060/
https://www.ncbi.nlm.nih.gov/pubmed/26509081
http://dx.doi.org/10.1155/2015/205716
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author Boima, Vincent
Ademola, Adebowale Dele
Odusola, Aina Olufemi
Agyekum, Francis
Nwafor, Chibuike Eze
Cole, Helen
Salako, Babatunde L.
Ogedegbe, Gbenga
Tayo, Bamidele O.
author_facet Boima, Vincent
Ademola, Adebowale Dele
Odusola, Aina Olufemi
Agyekum, Francis
Nwafor, Chibuike Eze
Cole, Helen
Salako, Babatunde L.
Ogedegbe, Gbenga
Tayo, Bamidele O.
author_sort Boima, Vincent
collection PubMed
description Background. Blood pressure (BP) control is poor among hypertensives in many parts of sub-Saharan Africa. A potentially modifiable factor for control of BP is medication nonadherence (MNA); our study therefore aimed to determine factors associated with MNA among hypertensives in Ghana and Nigeria. Methodology. We conducted a multicenter cross-sectional study. Patients were recruited from Korle-Bu Hospital (n = 120), Ghana; and University of Port Harcourt Teaching Hospital, (n = 73) Apapa General Hospital Lagos (n = 79) and University College Hospital Ibadan (n = 85), Nigeria. Results. 357 hypertensive patients (42.6% males) participated. MNA was found in 66.7%. Adherence showed correlation with depression (r = −0.208, P < 0.001), concern about medications (r = −0.0347, P = 0.002), and knowledge of hypertension (r = 0.14, P = 0.006). MNA was associated with formal education (P = 0.001) and use of herbal preparation (P = 0.014). MNA was found in 61.7% of uninsured participants versus 73.1% of insured participants (P = 0.032). Poor BP control was observed in 69.7% and there was significant association between MNA and poor BP control (P = 0.006). Conclusion. MNA is high among hypertensives in Ghana and Nigeria and is associated with depression, concern about hypertensive medications, formal education, and use of herbal preparations. The negative association between health insurance and MNA suggests interplay of other factors and needs further investigation.
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spelling pubmed-46100602015-10-27 Factors Associated with Medication Nonadherence among Hypertensives in Ghana and Nigeria Boima, Vincent Ademola, Adebowale Dele Odusola, Aina Olufemi Agyekum, Francis Nwafor, Chibuike Eze Cole, Helen Salako, Babatunde L. Ogedegbe, Gbenga Tayo, Bamidele O. Int J Hypertens Research Article Background. Blood pressure (BP) control is poor among hypertensives in many parts of sub-Saharan Africa. A potentially modifiable factor for control of BP is medication nonadherence (MNA); our study therefore aimed to determine factors associated with MNA among hypertensives in Ghana and Nigeria. Methodology. We conducted a multicenter cross-sectional study. Patients were recruited from Korle-Bu Hospital (n = 120), Ghana; and University of Port Harcourt Teaching Hospital, (n = 73) Apapa General Hospital Lagos (n = 79) and University College Hospital Ibadan (n = 85), Nigeria. Results. 357 hypertensive patients (42.6% males) participated. MNA was found in 66.7%. Adherence showed correlation with depression (r = −0.208, P < 0.001), concern about medications (r = −0.0347, P = 0.002), and knowledge of hypertension (r = 0.14, P = 0.006). MNA was associated with formal education (P = 0.001) and use of herbal preparation (P = 0.014). MNA was found in 61.7% of uninsured participants versus 73.1% of insured participants (P = 0.032). Poor BP control was observed in 69.7% and there was significant association between MNA and poor BP control (P = 0.006). Conclusion. MNA is high among hypertensives in Ghana and Nigeria and is associated with depression, concern about hypertensive medications, formal education, and use of herbal preparations. The negative association between health insurance and MNA suggests interplay of other factors and needs further investigation. Hindawi Publishing Corporation 2015 2015-10-05 /pmc/articles/PMC4610060/ /pubmed/26509081 http://dx.doi.org/10.1155/2015/205716 Text en Copyright © 2015 Vincent Boima et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Boima, Vincent
Ademola, Adebowale Dele
Odusola, Aina Olufemi
Agyekum, Francis
Nwafor, Chibuike Eze
Cole, Helen
Salako, Babatunde L.
Ogedegbe, Gbenga
Tayo, Bamidele O.
Factors Associated with Medication Nonadherence among Hypertensives in Ghana and Nigeria
title Factors Associated with Medication Nonadherence among Hypertensives in Ghana and Nigeria
title_full Factors Associated with Medication Nonadherence among Hypertensives in Ghana and Nigeria
title_fullStr Factors Associated with Medication Nonadherence among Hypertensives in Ghana and Nigeria
title_full_unstemmed Factors Associated with Medication Nonadherence among Hypertensives in Ghana and Nigeria
title_short Factors Associated with Medication Nonadherence among Hypertensives in Ghana and Nigeria
title_sort factors associated with medication nonadherence among hypertensives in ghana and nigeria
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4610060/
https://www.ncbi.nlm.nih.gov/pubmed/26509081
http://dx.doi.org/10.1155/2015/205716
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