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GEMMs as preclinical models for testing pancreatic cancer therapies
Pancreatic ductal adenocarcinoma is the most common form of pancreatic tumour, with a very limited survival rate and currently no available disease-modifying treatments. Despite recent advances in the production of genetically engineered mouse models (GEMMs), the development of new therapies for pan...
Autores principales: | Gopinathan, Aarthi, Morton, Jennifer P., Jodrell, Duncan I., Sansom, Owen J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4610236/ https://www.ncbi.nlm.nih.gov/pubmed/26438692 http://dx.doi.org/10.1242/dmm.021055 |
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