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Exploration of Cyanine Compounds as Selective Inhibitors of Protein Arginine Methyltransferases: Synthesis and Biological Evaluation

[Image: see text] Protein arginine methyltransferase 1 (PRMT1) is involved in many biological activities, such as gene transcription, signal transduction, and RNA processing. Overexpression of PRMT1 is related to cardiovascular diseases, kidney diseases, and cancers; therefore, selective PRMT1 inhib...

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Detalles Bibliográficos
Autores principales:	Hu, Hao, Owens, Eric A., Su, Hairui, Yan, Leilei, Levitz, Andrew, Zhao, Xinyang, Henary, Maged, Zheng, Yujun George
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2015
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4610307/ https://www.ncbi.nlm.nih.gov/pubmed/25559100 http://dx.doi.org/10.1021/jm501452j

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