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Association of Celiac Disease With Idiopathic Pulmonary Hemosiderosis; Lane Hamilton Syndrome
INTRODUCTION: Idiopathic Pulmonary Hemosiderosis (IPH) is a rare cause of alveolar hemorrhage, which is seen primarily in childhood. Celiac disease is defined as a chronic, immune-mediated enteropathy of the small intestine, caused by exposure to dietary gluten in genetically pre-disposed individual...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Kowsar
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4610337/ https://www.ncbi.nlm.nih.gov/pubmed/26495097 http://dx.doi.org/10.5812/ijp.3312 |
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author | Nacaroglu, Hikmet Tekin Sandal, Ozlem Sarac Bag, Ozlem Erdem, Semiha Bahceci Bekem Soylu, Ozlem Diniz, Gulden Ozturk, Aysel Can, Demet |
author_facet | Nacaroglu, Hikmet Tekin Sandal, Ozlem Sarac Bag, Ozlem Erdem, Semiha Bahceci Bekem Soylu, Ozlem Diniz, Gulden Ozturk, Aysel Can, Demet |
author_sort | Nacaroglu, Hikmet Tekin |
collection | PubMed |
description | INTRODUCTION: Idiopathic Pulmonary Hemosiderosis (IPH) is a rare cause of alveolar hemorrhage, which is seen primarily in childhood. Celiac disease is defined as a chronic, immune-mediated enteropathy of the small intestine, caused by exposure to dietary gluten in genetically pre-disposed individuals. Association of IPH and celiac disease is known as Lane Hamilton syndrome. There are limited number of case reports of this syndrome in literature. CASE PRESENTATION: Although there were no growth and developmental delay and gastrointestinal symptoms like chronic diarrhea, chronic constipation, vomiting, abdominal bloating and pain in the two patients with IPH, they were diagnosed with Lane Hamilton Syndrome. After initiation of gluten-free diet, their IPH symptoms disappeared and hemoglobin levels were observed to return to normal. CONCLUSIONS: Even if there were no gastrointestinal symptoms in a patient with IPH, celiac disease should be investigated. These patients may benefit from gluten free diet and IPH symptoms may disappear. |
format | Online Article Text |
id | pubmed-4610337 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Kowsar |
record_format | MEDLINE/PubMed |
spelling | pubmed-46103372015-10-22 Association of Celiac Disease With Idiopathic Pulmonary Hemosiderosis; Lane Hamilton Syndrome Nacaroglu, Hikmet Tekin Sandal, Ozlem Sarac Bag, Ozlem Erdem, Semiha Bahceci Bekem Soylu, Ozlem Diniz, Gulden Ozturk, Aysel Can, Demet Iran J Pediatr Case Report INTRODUCTION: Idiopathic Pulmonary Hemosiderosis (IPH) is a rare cause of alveolar hemorrhage, which is seen primarily in childhood. Celiac disease is defined as a chronic, immune-mediated enteropathy of the small intestine, caused by exposure to dietary gluten in genetically pre-disposed individuals. Association of IPH and celiac disease is known as Lane Hamilton syndrome. There are limited number of case reports of this syndrome in literature. CASE PRESENTATION: Although there were no growth and developmental delay and gastrointestinal symptoms like chronic diarrhea, chronic constipation, vomiting, abdominal bloating and pain in the two patients with IPH, they were diagnosed with Lane Hamilton Syndrome. After initiation of gluten-free diet, their IPH symptoms disappeared and hemoglobin levels were observed to return to normal. CONCLUSIONS: Even if there were no gastrointestinal symptoms in a patient with IPH, celiac disease should be investigated. These patients may benefit from gluten free diet and IPH symptoms may disappear. Kowsar 2015-10-06 2015-10 /pmc/articles/PMC4610337/ /pubmed/26495097 http://dx.doi.org/10.5812/ijp.3312 Text en Copyright © 2015, Growth & Development Research Center. http://creativecommons.org/licenses/by-nc/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited. |
spellingShingle | Case Report Nacaroglu, Hikmet Tekin Sandal, Ozlem Sarac Bag, Ozlem Erdem, Semiha Bahceci Bekem Soylu, Ozlem Diniz, Gulden Ozturk, Aysel Can, Demet Association of Celiac Disease With Idiopathic Pulmonary Hemosiderosis; Lane Hamilton Syndrome |
title | Association of Celiac Disease With Idiopathic Pulmonary Hemosiderosis; Lane Hamilton Syndrome |
title_full | Association of Celiac Disease With Idiopathic Pulmonary Hemosiderosis; Lane Hamilton Syndrome |
title_fullStr | Association of Celiac Disease With Idiopathic Pulmonary Hemosiderosis; Lane Hamilton Syndrome |
title_full_unstemmed | Association of Celiac Disease With Idiopathic Pulmonary Hemosiderosis; Lane Hamilton Syndrome |
title_short | Association of Celiac Disease With Idiopathic Pulmonary Hemosiderosis; Lane Hamilton Syndrome |
title_sort | association of celiac disease with idiopathic pulmonary hemosiderosis; lane hamilton syndrome |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4610337/ https://www.ncbi.nlm.nih.gov/pubmed/26495097 http://dx.doi.org/10.5812/ijp.3312 |
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