Cargando…

A polymorphism in a phosphotyrosine signalling motif of CD229 (Ly9, SLAMF3) alters SH2 domain binding and T‐cell activation

Signalling lymphocyte activation molecule (SLAM) family members regulate activation and inhibition in the innate and adaptive immune systems. Genome‐wide association studies identified their genetic locus (1q23) as highly polymorphic and associated with susceptibility to systemic lupus erythematosus...

Descripción completa

Detalles Bibliográficos
Autores principales:	Margraf, Stefanie, Garner, Lee I., Wilson, Timothy J., Brown, Marion H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2015
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4610628/ https://www.ncbi.nlm.nih.gov/pubmed/26221972 http://dx.doi.org/10.1111/imm.12513

Ejemplares similares

Specificity and regulation of phosphotyrosine signaling through SH2 domains
por: Marasco, Michelangelo, et al.
Publicado: (2020)

The Expression of the Hepatocyte SLAMF3 (CD229) Receptor Enhances the Hepatitis C Virus Infection
por: Cartier, Flora, et al.
Publicado: (2014)

Identification of SLAMF3 (CD229) as an Inhibitor of Hepatocellular Carcinoma Cell Proliferation and Tumour Progression
por: Marcq, Ingrid, et al.
Publicado: (2013)

Conformational Determinants of Phosphotyrosine Peptides Complexed with the Src SH2 Domain
por: Nachman, Joseph, et al.
Publicado: (2010)

CD229 (Ly9) a Novel Biomarker for B-Cell Malignancies and Multiple Myeloma
por: Roncador, Giovanna, et al.
Publicado: (2022)

Ly9 (CD229) Cell-Surface Receptor is Crucial for the Development of Spontaneous Autoantibody Production to Nuclear Antigens
por: de Salort, Jose, et al.
Publicado: (2013)

Selective Targeting of SH2 Domain–Phosphotyrosine Interactions of Src Family Tyrosine Kinases with Monobodies
por: Kükenshöner, Tim, et al.
Publicado: (2017)

Solution Structure of Tensin2 SH2 Domain and Its Phosphotyrosine-Independent Interaction with DLC-1
por: Dai, Kun, et al.
Publicado: (2011)

Phosphotyrosine Substrate Sequence Motifs for Dual Specificity Phosphatases
por: Zhao, Bryan M., et al.
Publicado: (2015)

(Arg)(9)-SH2 superbinder: a novel promising anticancer therapy to melanoma by blocking phosphotyrosine signaling
por: Liu, An-dong, et al.
Publicado: (2018)

IQGAP1 Is a Phosphotyrosine-Regulated Scaffold for SH2-Containing Proteins
por: Thines, Louise, et al.
Publicado: (2023)

Src family kinases interfere with dimerization of STAT5A through a phosphotyrosine-SH2 domain interaction
por: Fahrenkamp, Dirk, et al.
Publicado: (2015)

SLAMF6/Ly108 promotes the development of hepatocellular carcinoma via facilitating macrophage M2 polarization
por: Meng, Qi, et al.
Publicado: (2022)

Phosphotyrosine recognition domains: the typical, the atypical and the versatile
por: Kaneko, Tomonori, et al.
Publicado: (2012)

Negative Regulation of Humoral Immunity Due to Interplay between the SLAMF1, SLAMF5, and SLAMF6 Receptors
por: Wang, Ninghai, et al.
Publicado: (2015)

CRISPR-Mediated Triple Knockout of SLAMF1, SLAMF5 and SLAMF6 Supports Positive Signaling Roles in NKT Cell Development
por: Huang, Bonnie, et al.
Publicado: (2016)

Blockade of phosphotyrosine pathways suggesting SH2 superbinder as a novel therapy for pulmonary fibrosis
por: Wang, Meng, et al.
Publicado: (2022)

The phosphotyrosine-independent interaction of DLC-1 and the SH2 domain of cten regulates focal adhesion localization and growth suppression activity of DLC-1
por: Liao, Yi-Chun, et al.
Publicado: (2007)

Evaluation of the Interaction between Phosphohistidine Analogues and Phosphotyrosine Binding Domains
por: McAllister, Tom E, et al.
Publicado: (2014)

Evidence for the loss and recovery of SLAMF9 during human evolution: implications on Dollo’s law
por: Murphy, Maegan K., et al.
Publicado: (2021)

Recent advances in synthetic and medicinal chemistry of phosphotyrosine and phosphonate-based phosphotyrosine analogues
por: Makukhin, Nikolai, et al.
Publicado: (2020)

Tyr66 acts as a conformational switch in the closed-to-open transition of the SHP-2 N-SH2-domain phosphotyrosine-peptide binding cleft
por: Guvench, Olgun, et al.
Publicado: (2007)

TraPS-VarI: Identifying genetic variants altering phosphotyrosine based signalling motifs
por: Ulaganathan, Vijay Kumar
Publicado: (2020)

Cancer cell-expressed SLAMF7 is not required for CD47-mediated phagocytosis
por: He, Yuan, et al.
Publicado: (2019)

Ly9 (CD229) Antibody Targeting Depletes Marginal Zone and Germinal Center B Cells in Lymphoid Tissues and Reduces Salivary Gland Inflammation in a Mouse Model of Sjögren's Syndrome
por: Puñet-Ortiz, Joan, et al.
Publicado: (2018)

Responses to Microbial Challenges by SLAMF Receptors
por: van Driel, Boaz Job, et al.
Publicado: (2016)

Migration of Myeloid Cells during Inflammation Is Differentially Regulated by the Cell Surface Receptors Slamf1 and Slamf8
por: Wang, Guoxing, et al.
Publicado: (2015)

Advances in Understanding the Roles of CD244 (SLAMF4) in Immune Regulation and Associated Diseases
por: Sun, Lin, et al.
Publicado: (2021)

CRISPR-Mediated Slamf1(Δ/Δ) Slamf5(Δ/Δ) Slamf6(Δ/Δ) Triple Gene Disruption Reveals NKT Cell Defects but Not T Follicular Helper Cell Defects
por: Hu, Joyce K., et al.
Publicado: (2016)

Three alleles in the pat-3 locus of Caenorhabditis elegans: mutations in the membrane-distal NPxY phosphotyrosine motif
por: Hanna, Jacob, et al.
Publicado: (2020)

Crystal structures of p120RasGAP N-terminal SH2 domain in its apo form and in complex with a p190RhoGAP phosphotyrosine peptide
por: Jaber Chehayeb, Rachel, et al.
Publicado: (2019)

SLAMF6 compartmentalization enhances T cell functions
por: Gartshteyn, Yevgeniya, et al.
Publicado: (2022)

Earliest Holozoan Expansion of Phosphotyrosine Signaling
por: Suga, Hiroshi, et al.
Publicado: (2013)

Phosphotyrosine profiling of human cerebrospinal fluid
por: Sathe, Gajanan, et al.
Publicado: (2018)

Phosphotyrosine profiling of curcumin-induced signaling
por: Sathe, Gajanan, et al.
Publicado: (2016)

The SH3 regulatory domain of the hematopoietic cell kinase Hck binds ELMO via its polyproline motif
por: Awad, Rida, et al.
Publicado: (2015)

Correction: Crystal structures of p120RasGAP N-terminal SH2 domain in its apo form and in complex with a p190RhoGAP phosphotyrosine peptide
por: Jaber Chehayeb, Rachel, et al.
Publicado: (2020)

Short Linear Motifs recognized by SH2, SH3 and Ser/Thr Kinase domains are conserved in disordered protein regions
por: Ren, Siyuan, et al.
Publicado: (2008)

Genetically encoding phosphotyrosine and its nonhydrolyzable analog in bacteria
por: Luo, Xiaozhou, et al.
Publicado: (2017)

SLAMF6 clustering is required to augment T cell activation
por: Dragovich, Matthew A., et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_f0bnrbcq29dae8f65evlbnlfoj