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A human leucyl-tRNA synthetase as an anticancer target

Several aminoacyl-tRNA synthetases have been reported to be overexpressed for charging essential aminoacyl-tRNAs in many cancer types. In this study, we aimed to explore the potential role of leucyl-tRNA synthetase (LARS) as an anticancer target. MTT assay was performed to screen inhibitors to human...

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Detalles Bibliográficos
Autores principales:	Gao, Guangwei, Yao, Ying, Li, Kun, Mashausi, Dhahiri Saidi, Li, Dongsheng, Negi, Hema, Kamle, Suchitra, Chen, Hao, Wu, Zhenghua, Zhou, Huchen, Li, Dawei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2015
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4610879/ https://www.ncbi.nlm.nih.gov/pubmed/26508878 http://dx.doi.org/10.2147/OTT.S88873

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