Biomarkers for Primary Sjögren’s Syndrome

Primary Sjögren’s syndrome (pSS) is a systemic autoimmune disease with exocrine gland dysfunction and multi-organ involvement. Recent progress in understanding the pathogenesis of pSS offers an opportunity to find new biomarkers for the diagnosis and assessment of disease activity. Screening noninva...

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Detalles Bibliográficos
Autores principales: Chen, Weiqian, Cao, Heng, Lin, Jin, Olsen, Nancy, Zheng, Song Guo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4610966/
https://www.ncbi.nlm.nih.gov/pubmed/26362815
http://dx.doi.org/10.1016/j.gpb.2015.06.002
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author Chen, Weiqian
Cao, Heng
Lin, Jin
Olsen, Nancy
Zheng, Song Guo
author_facet Chen, Weiqian
Cao, Heng
Lin, Jin
Olsen, Nancy
Zheng, Song Guo
author_sort Chen, Weiqian
collection PubMed
description Primary Sjögren’s syndrome (pSS) is a systemic autoimmune disease with exocrine gland dysfunction and multi-organ involvement. Recent progress in understanding the pathogenesis of pSS offers an opportunity to find new biomarkers for the diagnosis and assessment of disease activity. Screening noninvasive biomarkers from the saliva and tears has significant potential. The need for specific and sensitive biomarker candidates in pSS is significant. This review aims to summarize recent advances in the identification of biomarkers of Sjögren syndrome, trying to identify reliable, sensitive, and specific biomarkers that can be used to guide treatment decisions.
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spelling pubmed-46109662015-11-20 Biomarkers for Primary Sjögren’s Syndrome Chen, Weiqian Cao, Heng Lin, Jin Olsen, Nancy Zheng, Song Guo Genomics Proteomics Bioinformatics Review Primary Sjögren’s syndrome (pSS) is a systemic autoimmune disease with exocrine gland dysfunction and multi-organ involvement. Recent progress in understanding the pathogenesis of pSS offers an opportunity to find new biomarkers for the diagnosis and assessment of disease activity. Screening noninvasive biomarkers from the saliva and tears has significant potential. The need for specific and sensitive biomarker candidates in pSS is significant. This review aims to summarize recent advances in the identification of biomarkers of Sjögren syndrome, trying to identify reliable, sensitive, and specific biomarkers that can be used to guide treatment decisions. Elsevier 2015-08 2015-09-08 /pmc/articles/PMC4610966/ /pubmed/26362815 http://dx.doi.org/10.1016/j.gpb.2015.06.002 Text en © 2015 The Authors http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Chen, Weiqian
Cao, Heng
Lin, Jin
Olsen, Nancy
Zheng, Song Guo
Biomarkers for Primary Sjögren’s Syndrome
title Biomarkers for Primary Sjögren’s Syndrome
title_full Biomarkers for Primary Sjögren’s Syndrome
title_fullStr Biomarkers for Primary Sjögren’s Syndrome
title_full_unstemmed Biomarkers for Primary Sjögren’s Syndrome
title_short Biomarkers for Primary Sjögren’s Syndrome
title_sort biomarkers for primary sjögren’s syndrome
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4610966/
https://www.ncbi.nlm.nih.gov/pubmed/26362815
http://dx.doi.org/10.1016/j.gpb.2015.06.002
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