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Identification of a Natural Viral RNA Motif That Optimizes Sensing of Viral RNA by RIG-I
Stimulation of the antiviral response depends on the sensing of viral pathogen-associated molecular patterns (PAMPs) by specialized cellular proteins. During infection with RNA viruses, 5′-di- or -triphosphates accompanying specific single or double-stranded RNA motifs trigger signaling of intracell...
Autores principales: | Xu, Jie, Mercado-López, Xiomara, Grier, Jennifer T., Kim, Won-keun, Chun, Lauren F., Irvine, Edward B., Del Toro Duany, Yoandris, Kell, Alison, Hur, Sun, Gale, Michael, Raj, Arjun, López, Carolina B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Microbiology
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4611036/ https://www.ncbi.nlm.nih.gov/pubmed/26443454 http://dx.doi.org/10.1128/mBio.01265-15 |
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