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Insufficient Acidification of Autophagosomes Facilitates Group A Streptococcus Survival and Growth in Endothelial Cells

Group A streptococcus (GAS) is an important human pathogen, and its invasion via blood vessels is critically important in serious events such as bacteremia or multiorgan failure. Although GAS was identified as an extracellular bacterium, the internalization of GAS into nonphagocytic cells may provid...

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Detalles Bibliográficos
Autores principales: Lu, Shiou-Ling, Kuo, Chih-Feng, Chen, Hao-Wen, Yang, Yi-Shuan, Liu, Ching-Chuan, Anderson, Robert, Wu, Jiunn-Jong, Lin, Yee-Shin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4611045/
https://www.ncbi.nlm.nih.gov/pubmed/26419882
http://dx.doi.org/10.1128/mBio.01435-15

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