Cargando…
Insufficient Acidification of Autophagosomes Facilitates Group A Streptococcus Survival and Growth in Endothelial Cells
Group A streptococcus (GAS) is an important human pathogen, and its invasion via blood vessels is critically important in serious events such as bacteremia or multiorgan failure. Although GAS was identified as an extracellular bacterium, the internalization of GAS into nonphagocytic cells may provid...
Autores principales: | Lu, Shiou-Ling, Kuo, Chih-Feng, Chen, Hao-Wen, Yang, Yi-Shuan, Liu, Ching-Chuan, Anderson, Robert, Wu, Jiunn-Jong, Lin, Yee-Shin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Microbiology
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4611045/ https://www.ncbi.nlm.nih.gov/pubmed/26419882 http://dx.doi.org/10.1128/mBio.01435-15 |
Ejemplares similares
-
NAD-Glycohydrolase Depletes Intracellular NAD(+) and Inhibits Acidification of Autophagosomes to Enhance Multiplication of Group A Streptococcus in Endothelial Cells
por: Hsieh, Cheng-Lu, et al.
Publicado: (2018) -
VEGF-Mediated Augmentation of Autophagic and Lysosomal Activity in Endothelial Cells Defends against Intracellular Streptococcus pyogenes
por: Lu, Shiou-Ling, et al.
Publicado: (2022) -
Autophagosome–lysosome fusion is independent of V-ATPase-mediated acidification
por: Mauvezin, Caroline, et al.
Publicado: (2015) -
Group A Streptococcus Induces LAPosomes via SLO/β1 Integrin/NOX2/ROS Pathway in Endothelial Cells That Are Ineffective in Bacterial Killing and Suppress Xenophagy
por: Cheng, Yi-Lin, et al.
Publicado: (2019) -
Erratum for Cheng et al., “Group A Streptococcus Induces LAPosomes via SLO/β1 Integrin/NOX2/ROS Pathway in Endothelial Cells That Are Ineffective in Bacterial Killing and Suppress Xenophagy”
por: Cheng, Yi-Lin, et al.
Publicado: (2021)