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Quantitative time-resolved analysis reveals intricate, differential regulation of standard- and immuno-proteasomes

Proteasomal protein degradation is a key determinant of protein half-life and hence of cellular processes ranging from basic metabolism to a host of immunological processes. Despite its importance the mechanisms regulating proteasome activity are only incompletely understood. Here we use an iterativ...

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Detalles Bibliográficos
Autores principales:	Liepe, Juliane, Holzhütter, Hermann-Georg, Bellavista, Elena, Kloetzel, Peter M, Stumpf, Michael PH, Mishto, Michele
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2015
Materias:	Biophysics and Structural Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4611054/ https://www.ncbi.nlm.nih.gov/pubmed/26393687 http://dx.doi.org/10.7554/eLife.07545

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