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T-cell activation or tolerization: the Yin and Yang of bacterial superantigens
Bacterial superantigens (SAg) are exotoxins from pathogens which interact with innate and adaptive immune cells. The paradox that SAgs cause activation and inactivation/anergy of T-cells was soon recognized. The structural and molecular events following SAg binding to antigen presenting cells (APCs)...
Autores principales: | Sähr, Aline, Förmer, Sandra, Hildebrand, Dagmar, Heeg, Klaus |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4611159/ https://www.ncbi.nlm.nih.gov/pubmed/26539181 http://dx.doi.org/10.3389/fmicb.2015.01153 |
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