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T-cell activation or tolerization: the Yin and Yang of bacterial superantigens

Bacterial superantigens (SAg) are exotoxins from pathogens which interact with innate and adaptive immune cells. The paradox that SAgs cause activation and inactivation/anergy of T-cells was soon recognized. The structural and molecular events following SAg binding to antigen presenting cells (APCs)...

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Detalles Bibliográficos
Autores principales: Sähr, Aline, Förmer, Sandra, Hildebrand, Dagmar, Heeg, Klaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4611159/
https://www.ncbi.nlm.nih.gov/pubmed/26539181
http://dx.doi.org/10.3389/fmicb.2015.01153

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