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Telmisartan and Insulin Resistance in HIV (TAILoR): protocol for a dose-ranging phase II randomised open-labelled trial of telmisartan as a strategy for the reduction of insulin resistance in HIV-positive individuals on combination antiretroviral therapy
INTRODUCTION: Telmisartan, an angiotensin receptor blocker, has beneficial effects on insulin resistance and cardiovascular health in non-HIV populations. This trial will evaluate whether telmisartan can reduce insulin resistance in HIV-positive individuals on combination antiretroviral therapy. MET...
Autores principales: | Pushpakom, Sudeep P, Taylor, Claire, Kolamunnage-Dona, Ruwanthi, Spowart, Catherine, Vora, Jiten, García-Fiñana, Marta, Kemp, Graham J, Whitehead, John, Jaki, Thomas, Khoo, Saye, Williamson, Paula, Pirmohamed, Munir |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4611177/ https://www.ncbi.nlm.nih.gov/pubmed/26474943 http://dx.doi.org/10.1136/bmjopen-2015-009566 |
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