Characterization of the Whole-Genome Sequence of an H3N6 Avian Influenza Virus, Isolated from a Domestic Duck in Guangxi, Southern China

A field strain of H3N6 avian influenza virus (AIV), A/duck/Guangxi/175D12/2014(H3N6), was isolated from a native duck in Guangxi Province, southern China, in 2014. All of the eight AIV gene segments were sequenced, and sequence results revealed that there were 11 amino acid deletions at the NA stalk...

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Autores principales: Liu, Tingting, Xie, Zhixun, Luo, Sisi, Xie, Liji, Deng, Xianwen, Xie, Zhiqing, Huang, Li, Huang, Jiaoling, Zhang, Yanfang, Zeng, Tingting, Wang, Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2015
Materias:
Viruses
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4611686/
https://www.ncbi.nlm.nih.gov/pubmed/26472834
http://dx.doi.org/10.1128/genomeA.01190-15
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author Liu, Tingting
Xie, Zhixun
Luo, Sisi
Xie, Liji
Deng, Xianwen
Xie, Zhiqing
Huang, Li
Huang, Jiaoling
Zhang, Yanfang
Zeng, Tingting
Wang, Sheng
author_facet Liu, Tingting
Xie, Zhixun
Luo, Sisi
Xie, Liji
Deng, Xianwen
Xie, Zhiqing
Huang, Li
Huang, Jiaoling
Zhang, Yanfang
Zeng, Tingting
Wang, Sheng
author_sort Liu, Tingting
collection PubMed
description A field strain of H3N6 avian influenza virus (AIV), A/duck/Guangxi/175D12/2014(H3N6), was isolated from a native duck in Guangxi Province, southern China, in 2014. All of the eight AIV gene segments were sequenced, and sequence results revealed that there were 11 amino acid deletions at the NA stalk region. The NA, PB2, and NP genes showed highest homology to H5N6 AIV, and the PA gene showed highest homology to H7N2 AIV. Phylogenetic analysis indicated that the eight AIV gene segments belonged to the Eurasian lineage. These findings provide scientific evidence of possible or potential mutations of H3N6 AIV circulating in waterfowl in southern China.
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spelling pubmed-46116862015-10-25 Characterization of the Whole-Genome Sequence of an H3N6 Avian Influenza Virus, Isolated from a Domestic Duck in Guangxi, Southern China Liu, Tingting Xie, Zhixun Luo, Sisi Xie, Liji Deng, Xianwen Xie, Zhiqing Huang, Li Huang, Jiaoling Zhang, Yanfang Zeng, Tingting Wang, Sheng Genome Announc Viruses A field strain of H3N6 avian influenza virus (AIV), A/duck/Guangxi/175D12/2014(H3N6), was isolated from a native duck in Guangxi Province, southern China, in 2014. All of the eight AIV gene segments were sequenced, and sequence results revealed that there were 11 amino acid deletions at the NA stalk region. The NA, PB2, and NP genes showed highest homology to H5N6 AIV, and the PA gene showed highest homology to H7N2 AIV. Phylogenetic analysis indicated that the eight AIV gene segments belonged to the Eurasian lineage. These findings provide scientific evidence of possible or potential mutations of H3N6 AIV circulating in waterfowl in southern China. American Society for Microbiology 2015-10-15 /pmc/articles/PMC4611686/ /pubmed/26472834 http://dx.doi.org/10.1128/genomeA.01190-15 Text en Copyright © 2015 Liu et al. http://creativecommons.org/licenses/by/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution 3.0 Unported license (http://creativecommons.org/licenses/by/3.0/) .
spellingShingle Viruses
Liu, Tingting
Xie, Zhixun
Luo, Sisi
Xie, Liji
Deng, Xianwen
Xie, Zhiqing
Huang, Li
Huang, Jiaoling
Zhang, Yanfang
Zeng, Tingting
Wang, Sheng
Characterization of the Whole-Genome Sequence of an H3N6 Avian Influenza Virus, Isolated from a Domestic Duck in Guangxi, Southern China
title Characterization of the Whole-Genome Sequence of an H3N6 Avian Influenza Virus, Isolated from a Domestic Duck in Guangxi, Southern China
title_full Characterization of the Whole-Genome Sequence of an H3N6 Avian Influenza Virus, Isolated from a Domestic Duck in Guangxi, Southern China
title_fullStr Characterization of the Whole-Genome Sequence of an H3N6 Avian Influenza Virus, Isolated from a Domestic Duck in Guangxi, Southern China
title_full_unstemmed Characterization of the Whole-Genome Sequence of an H3N6 Avian Influenza Virus, Isolated from a Domestic Duck in Guangxi, Southern China
title_short Characterization of the Whole-Genome Sequence of an H3N6 Avian Influenza Virus, Isolated from a Domestic Duck in Guangxi, Southern China
title_sort characterization of the whole-genome sequence of an h3n6 avian influenza virus, isolated from a domestic duck in guangxi, southern china
topic Viruses
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4611686/
https://www.ncbi.nlm.nih.gov/pubmed/26472834
http://dx.doi.org/10.1128/genomeA.01190-15
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