Rnd3 haploinsufficient mice are predisposed to hemodynamic stress and develop apoptotic cardiomyopathy with heart failure

Rho family guanosine triphosphatase (GTPase) 3 (Rnd3), a member of the small Rho GTPase family, has been suggested to regulate cell actin cytoskeleton dynamics, cell migration, and apoptosis through the Rho kinase-dependent signaling pathway. The biological function of Rnd3 in the heart is unknown....

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Detalles Bibliográficos
Autores principales: Yue, X, Yang, X, Lin, X, Yang, T, Yi, X, Dai, Y, Guo, J, Li, T, Shi, J, Wei, L, Fan, G-C, Chen, C, Chang, J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4611712/
https://www.ncbi.nlm.nih.gov/pubmed/24901055
http://dx.doi.org/10.1038/cddis.2014.235

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