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Genetic deficiency of neuronal RAGE protects against AGE-induced synaptic injury

Synaptic dysfunction and degeneration is an early pathological feature of aging and age-related diseases, including Alzheimer's disease (AD). Aging is associated with increased generation and deposition of advanced glycation endproducts (AGEs), resulting from nonenzymatic glycation (or oxidatio...

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Detalles Bibliográficos
Autores principales:	Zhang, Hongju, Wang, Yongfu, Yan, Shijun, Du, Fang, Wu, Long, Yan, Shiqiang, Yan, Shirley S
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2014
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4611721/ https://www.ncbi.nlm.nih.gov/pubmed/24922072 http://dx.doi.org/10.1038/cddis.2014.248

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