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Bcl-xL controls a switch between cell death modes during mitotic arrest

Antimitotic agents such as microtubule inhibitors (paclitaxel) are widely used in cancer therapy while new agents blocking mitosis onset are currently in development. All these agents impose a prolonged mitotic arrest in cancer cells that relies on sustained activation of the spindle assembly checkp...

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Detalles Bibliográficos
Autores principales: Bah, N, Maillet, L, Ryan, J, Dubreil, S, Gautier, F, Letai, A, Juin, P, Barillé-Nion, S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4611724/
https://www.ncbi.nlm.nih.gov/pubmed/24922075
http://dx.doi.org/10.1038/cddis.2014.251