Bcl-xL controls a switch between cell death modes during mitotic arrest

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Antimitotic agents such as microtubule inhibitors (paclitaxel) are widely used in cancer therapy while new agents blocking mitosis onset are currently in development. All these agents impose a prolonged mitotic arrest in cancer cells that relies on sustained activation of the spindle assembly checkp...

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Detalles Bibliográficos
Autores principales: Bah, N, Maillet, L, Ryan, J, Dubreil, S, Gautier, F, Letai, A, Juin, P, Barillé-Nion, S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4611724/
https://www.ncbi.nlm.nih.gov/pubmed/24922075
http://dx.doi.org/10.1038/cddis.2014.251
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