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Speaking in Alzheimer’s Disease, is That an Early Sign? Importance of Changes in Language Abilities in Alzheimer’s Disease

It is known that Alzheimer’s disease (AD) influences the temporal characteristics of spontaneous speech. These phonetical changes are present even in mild AD. Based on this, the question arises whether an examination based on language analysis could help the early diagnosis of AD and if so, which la...

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Autores principales: Szatloczki, Greta, Hoffmann, Ildiko, Vincze, Veronika, Kalman, Janos, Pakaski, Magdolna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4611852/
https://www.ncbi.nlm.nih.gov/pubmed/26539107
http://dx.doi.org/10.3389/fnagi.2015.00195
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author Szatloczki, Greta
Hoffmann, Ildiko
Vincze, Veronika
Kalman, Janos
Pakaski, Magdolna
author_facet Szatloczki, Greta
Hoffmann, Ildiko
Vincze, Veronika
Kalman, Janos
Pakaski, Magdolna
author_sort Szatloczki, Greta
collection PubMed
description It is known that Alzheimer’s disease (AD) influences the temporal characteristics of spontaneous speech. These phonetical changes are present even in mild AD. Based on this, the question arises whether an examination based on language analysis could help the early diagnosis of AD and if so, which language and speech characteristics can identify AD in its early stage. The purpose of this article is to summarize the relation between prodromal and manifest AD and language functions and language domains. Based on our research, we are inclined to claim that AD can be more sensitively detected with the help of a linguistic analysis than with other cognitive examinations. The temporal characteristics of spontaneous speech, such as speech tempo, number of pauses in speech, and their length are sensitive detectors of the early stage of the disease, which enables an early simple linguistic screening for AD. However, knowledge about the unique features of the language problems associated with different dementia variants still has to be improved and refined.
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spelling pubmed-46118522015-11-04 Speaking in Alzheimer’s Disease, is That an Early Sign? Importance of Changes in Language Abilities in Alzheimer’s Disease Szatloczki, Greta Hoffmann, Ildiko Vincze, Veronika Kalman, Janos Pakaski, Magdolna Front Aging Neurosci Neuroscience It is known that Alzheimer’s disease (AD) influences the temporal characteristics of spontaneous speech. These phonetical changes are present even in mild AD. Based on this, the question arises whether an examination based on language analysis could help the early diagnosis of AD and if so, which language and speech characteristics can identify AD in its early stage. The purpose of this article is to summarize the relation between prodromal and manifest AD and language functions and language domains. Based on our research, we are inclined to claim that AD can be more sensitively detected with the help of a linguistic analysis than with other cognitive examinations. The temporal characteristics of spontaneous speech, such as speech tempo, number of pauses in speech, and their length are sensitive detectors of the early stage of the disease, which enables an early simple linguistic screening for AD. However, knowledge about the unique features of the language problems associated with different dementia variants still has to be improved and refined. Frontiers Media S.A. 2015-10-20 /pmc/articles/PMC4611852/ /pubmed/26539107 http://dx.doi.org/10.3389/fnagi.2015.00195 Text en Copyright © 2015 Szatloczki, Hoffmann, Vincze, Kalman and Pakaski. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neuroscience
Szatloczki, Greta
Hoffmann, Ildiko
Vincze, Veronika
Kalman, Janos
Pakaski, Magdolna
Speaking in Alzheimer’s Disease, is That an Early Sign? Importance of Changes in Language Abilities in Alzheimer’s Disease
title Speaking in Alzheimer’s Disease, is That an Early Sign? Importance of Changes in Language Abilities in Alzheimer’s Disease
title_full Speaking in Alzheimer’s Disease, is That an Early Sign? Importance of Changes in Language Abilities in Alzheimer’s Disease
title_fullStr Speaking in Alzheimer’s Disease, is That an Early Sign? Importance of Changes in Language Abilities in Alzheimer’s Disease
title_full_unstemmed Speaking in Alzheimer’s Disease, is That an Early Sign? Importance of Changes in Language Abilities in Alzheimer’s Disease
title_short Speaking in Alzheimer’s Disease, is That an Early Sign? Importance of Changes in Language Abilities in Alzheimer’s Disease
title_sort speaking in alzheimer’s disease, is that an early sign? importance of changes in language abilities in alzheimer’s disease
topic Neuroscience
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4611852/
https://www.ncbi.nlm.nih.gov/pubmed/26539107
http://dx.doi.org/10.3389/fnagi.2015.00195
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