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The wonderous chaperones: A highlight on therapeutics of cancer and potentially malignant disorders

Diverse environmental and physiological factors are known to induce the transcription of a set of genes encoding special protective molecules known as “molecular chaperones” within our cells. Literature abounds in evidence regarding the varied roles; these “guides” can effectively perform in our sys...

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Detalles Bibliográficos
Autores principales: Tyagi, Nutan, Tyagi, Rishi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4611931/
https://www.ncbi.nlm.nih.gov/pubmed/26604499
http://dx.doi.org/10.4103/0973-029X.164535
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author Tyagi, Nutan
Tyagi, Rishi
author_facet Tyagi, Nutan
Tyagi, Rishi
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description Diverse environmental and physiological factors are known to induce the transcription of a set of genes encoding special protective molecules known as “molecular chaperones” within our cells. Literature abounds in evidence regarding the varied roles; these “guides” can effectively perform in our system. Highly conserved through evolution, from the prokaryotes to the eukaryotes, these make perfect study tools for verifying their role in both the pathogenesis as well as the therapeutics of varied neurodegenerative, autoimmune and potentially malignant disorders and varied cancer states. We present a concise review of this ever dynamic molecule, highlighting the probable role in a potentially malignant disorder, oral lichen planus.
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spelling pubmed-46119312015-11-24 The wonderous chaperones: A highlight on therapeutics of cancer and potentially malignant disorders Tyagi, Nutan Tyagi, Rishi J Oral Maxillofac Pathol Review Article Diverse environmental and physiological factors are known to induce the transcription of a set of genes encoding special protective molecules known as “molecular chaperones” within our cells. Literature abounds in evidence regarding the varied roles; these “guides” can effectively perform in our system. Highly conserved through evolution, from the prokaryotes to the eukaryotes, these make perfect study tools for verifying their role in both the pathogenesis as well as the therapeutics of varied neurodegenerative, autoimmune and potentially malignant disorders and varied cancer states. We present a concise review of this ever dynamic molecule, highlighting the probable role in a potentially malignant disorder, oral lichen planus. Medknow Publications & Media Pvt Ltd 2015 /pmc/articles/PMC4611931/ /pubmed/26604499 http://dx.doi.org/10.4103/0973-029X.164535 Text en Copyright: © Journal of Oral and Maxillofacial Pathology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms
spellingShingle Review Article
Tyagi, Nutan
Tyagi, Rishi
The wonderous chaperones: A highlight on therapeutics of cancer and potentially malignant disorders
title The wonderous chaperones: A highlight on therapeutics of cancer and potentially malignant disorders
title_full The wonderous chaperones: A highlight on therapeutics of cancer and potentially malignant disorders
title_fullStr The wonderous chaperones: A highlight on therapeutics of cancer and potentially malignant disorders
title_full_unstemmed The wonderous chaperones: A highlight on therapeutics of cancer and potentially malignant disorders
title_short The wonderous chaperones: A highlight on therapeutics of cancer and potentially malignant disorders
title_sort wonderous chaperones: a highlight on therapeutics of cancer and potentially malignant disorders
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4611931/
https://www.ncbi.nlm.nih.gov/pubmed/26604499
http://dx.doi.org/10.4103/0973-029X.164535
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