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The wonderous chaperones: A highlight on therapeutics of cancer and potentially malignant disorders
Diverse environmental and physiological factors are known to induce the transcription of a set of genes encoding special protective molecules known as “molecular chaperones” within our cells. Literature abounds in evidence regarding the varied roles; these “guides” can effectively perform in our sys...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4611931/ https://www.ncbi.nlm.nih.gov/pubmed/26604499 http://dx.doi.org/10.4103/0973-029X.164535 |
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author | Tyagi, Nutan Tyagi, Rishi |
author_facet | Tyagi, Nutan Tyagi, Rishi |
author_sort | Tyagi, Nutan |
collection | PubMed |
description | Diverse environmental and physiological factors are known to induce the transcription of a set of genes encoding special protective molecules known as “molecular chaperones” within our cells. Literature abounds in evidence regarding the varied roles; these “guides” can effectively perform in our system. Highly conserved through evolution, from the prokaryotes to the eukaryotes, these make perfect study tools for verifying their role in both the pathogenesis as well as the therapeutics of varied neurodegenerative, autoimmune and potentially malignant disorders and varied cancer states. We present a concise review of this ever dynamic molecule, highlighting the probable role in a potentially malignant disorder, oral lichen planus. |
format | Online Article Text |
id | pubmed-4611931 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-46119312015-11-24 The wonderous chaperones: A highlight on therapeutics of cancer and potentially malignant disorders Tyagi, Nutan Tyagi, Rishi J Oral Maxillofac Pathol Review Article Diverse environmental and physiological factors are known to induce the transcription of a set of genes encoding special protective molecules known as “molecular chaperones” within our cells. Literature abounds in evidence regarding the varied roles; these “guides” can effectively perform in our system. Highly conserved through evolution, from the prokaryotes to the eukaryotes, these make perfect study tools for verifying their role in both the pathogenesis as well as the therapeutics of varied neurodegenerative, autoimmune and potentially malignant disorders and varied cancer states. We present a concise review of this ever dynamic molecule, highlighting the probable role in a potentially malignant disorder, oral lichen planus. Medknow Publications & Media Pvt Ltd 2015 /pmc/articles/PMC4611931/ /pubmed/26604499 http://dx.doi.org/10.4103/0973-029X.164535 Text en Copyright: © Journal of Oral and Maxillofacial Pathology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms |
spellingShingle | Review Article Tyagi, Nutan Tyagi, Rishi The wonderous chaperones: A highlight on therapeutics of cancer and potentially malignant disorders |
title | The wonderous chaperones: A highlight on therapeutics of cancer and potentially malignant disorders |
title_full | The wonderous chaperones: A highlight on therapeutics of cancer and potentially malignant disorders |
title_fullStr | The wonderous chaperones: A highlight on therapeutics of cancer and potentially malignant disorders |
title_full_unstemmed | The wonderous chaperones: A highlight on therapeutics of cancer and potentially malignant disorders |
title_short | The wonderous chaperones: A highlight on therapeutics of cancer and potentially malignant disorders |
title_sort | wonderous chaperones: a highlight on therapeutics of cancer and potentially malignant disorders |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4611931/ https://www.ncbi.nlm.nih.gov/pubmed/26604499 http://dx.doi.org/10.4103/0973-029X.164535 |
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