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The Mendelian colorectal cancer syndromes
A small minority of colorectal cancers (CRCs) (≤5%) are caused by a single, inherited faulty gene. These diseases, the Mendelian colorectal cancer (CRC) syndromes, have been central to our understanding of colorectal carcinogenesis in general. Most of the approximately 13 high-penetrance genes that...
Autor principal: | Tomlinson, Ian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4611988/ https://www.ncbi.nlm.nih.gov/pubmed/26169059 http://dx.doi.org/10.1177/0004563215597944 |
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