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Replacement of brain-resident myeloid cells does not alter cerebral amyloid-β deposition in mouse models of Alzheimer’s disease

Immune cells of myeloid lineage are encountered in the Alzheimer’s disease (AD) brain, where they cluster around amyloid-β plaques. However, assigning functional roles to myeloid cell subtypes has been problematic, and the potential for peripheral myeloid cells to alleviate AD pathology remains uncl...

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Detalles Bibliográficos
Autores principales:	Varvel, Nicholas H., Grathwohl, Stefan A., Degenhardt, Karoline, Resch, Claudia, Bosch, Andrea, Jucker, Mathias, Neher, Jonas J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2015
Materias:	Brief Definitive Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4612086/ https://www.ncbi.nlm.nih.gov/pubmed/26458770 http://dx.doi.org/10.1084/jem.20150478

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