Impact of peripheral myeloid cells on amyloid-β pathology in Alzheimer’s disease–like mice

Although central nervous system–resident microglia are believed to be ineffective at phagocytosing and clearing amyloid-β (Aβ), a major pathological hallmark of Alzheimer’s disease (AD), it has been suggested that peripheral myeloid cells constitute a heterogeneous cell population with greater Aβ-cl...

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Detalles Bibliográficos
Autores principales: Prokop, Stefan, Miller, Kelly R., Drost, Natalia, Handrick, Susann, Mathur, Vidhu, Luo, Jian, Wegner, Anja, Wyss-Coray, Tony, Heppner, Frank L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
Brief Definitive Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4612091/
https://www.ncbi.nlm.nih.gov/pubmed/26458768
http://dx.doi.org/10.1084/jem.20150479

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