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Unique and redundant functions of NKp46(+) ILC3s in models of intestinal inflammation
Group 3 ILCs (ILC3s) are innate sources of IL-22 and IL-17 and include lymphoid tissue-inducer (LTi)-like and NKp46(+) subsets. Both depend on RORγt and aryl hydrocarbon receptor, but NKp46(+)ILC3s also require Notch and T-bet for their development and are transcriptionally distinct. The extent to w...
Autores principales: | Song, Christina, Lee, Jacob S., Gilfillan, Susan, Robinette, Michelle L., Newberry, Rodney D., Stappenbeck, Thaddeus S., Mack, Matthias, Cella, Marina, Colonna, Marco |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4612098/ https://www.ncbi.nlm.nih.gov/pubmed/26458769 http://dx.doi.org/10.1084/jem.20151403 |
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