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A delay prior to mitotic entry triggers caspase 8-dependent cell death in p53-deficient Hela and HCT-116 cells

Stathmin/Oncoprotein 18, a microtubule destabilizing protein, is required for survival of p53-deficient cells. Stathmin-depleted cells are slower to enter mitosis, but whether delayed mitotic entry triggers cell death or whether stathmin has a separate pro-survival function was unknown. To test thes...

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Detalles Bibliográficos
Autores principales:	Silva, Victoria C, Plooster, Melissa, Leung, Jessica C, Cassimeris, Lynne
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2015
Materias:	Reports
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4612104/ https://www.ncbi.nlm.nih.gov/pubmed/25602147 http://dx.doi.org/10.1080/15384101.2015.1007781

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