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Regio- and stereoselective synthesis of benzothiazolo-pyrimidinones via an NHC-catalyzed Mannich/lactamization domino reaction

An NHC-catalyzed regio- and stereoselective Mannich/lactamization domino reaction of N-(benzothiazolyl)imines with α-chloroaldehydes has been developed. This new protocol provides a facile approach for the asymmetric synthesis of benzothiazolo-pyrimidinones and a pyrrolo[1,2-a]indolone in moderate t...

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Detalles Bibliográficos
Autores principales:	Ni, Qijian, Song, Xiaoxiao, Xiong, Jiawen, Raabe, Gerhard, Enders, Dieter
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Royal Society of Chemistry 2015
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4612130/ https://www.ncbi.nlm.nih.gov/pubmed/25476422 http://dx.doi.org/10.1039/c4cc08594a

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