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A loopy view of telomere evolution
About a decade ago, I proposed that t-loops, the lariat structures adopted by many eukaryotic telomeres, could explain how the transition from circular to linear chromosomes was successfully negotiated by early eukaryotes. Here I reconsider this loopy hypothesis in the context of the idea that eukar...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4612135/ https://www.ncbi.nlm.nih.gov/pubmed/26539211 http://dx.doi.org/10.3389/fgene.2015.00321 |
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author | de Lange, Titia |
author_facet | de Lange, Titia |
author_sort | de Lange, Titia |
collection | PubMed |
description | About a decade ago, I proposed that t-loops, the lariat structures adopted by many eukaryotic telomeres, could explain how the transition from circular to linear chromosomes was successfully negotiated by early eukaryotes. Here I reconsider this loopy hypothesis in the context of the idea that eukaryotes evolved through a period of genome invasion by Group II introns. |
format | Online Article Text |
id | pubmed-4612135 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-46121352015-11-04 A loopy view of telomere evolution de Lange, Titia Front Genet Genetics About a decade ago, I proposed that t-loops, the lariat structures adopted by many eukaryotic telomeres, could explain how the transition from circular to linear chromosomes was successfully negotiated by early eukaryotes. Here I reconsider this loopy hypothesis in the context of the idea that eukaryotes evolved through a period of genome invasion by Group II introns. Frontiers Media S.A. 2015-10-20 /pmc/articles/PMC4612135/ /pubmed/26539211 http://dx.doi.org/10.3389/fgene.2015.00321 Text en Copyright © 2015 de Lange. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Genetics de Lange, Titia A loopy view of telomere evolution |
title | A loopy view of telomere evolution |
title_full | A loopy view of telomere evolution |
title_fullStr | A loopy view of telomere evolution |
title_full_unstemmed | A loopy view of telomere evolution |
title_short | A loopy view of telomere evolution |
title_sort | loopy view of telomere evolution |
topic | Genetics |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4612135/ https://www.ncbi.nlm.nih.gov/pubmed/26539211 http://dx.doi.org/10.3389/fgene.2015.00321 |
work_keys_str_mv | AT delangetitia aloopyviewoftelomereevolution AT delangetitia loopyviewoftelomereevolution |