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Differential capacity of human interleukin-4 and interferon-α monocyte-derived dendritic cells for cross-presentation of free versus cell-associated antigen
Dendritic cells (DC) vaccination is a potent therapeutic approach for inducing tumor-directed immunity, but challenges remain. One of the particular interest is the induction of an immune response targeting multiple (unknown) tumor-associated antigens (TAA), which requires a polyvalent source of TAA...
Autores principales: | Ruben, Jurjen M., Bontkes, Hetty J., Westers, Theresia M., Hooijberg, Erik, Ossenkoppele, Gert J., de Gruijl, Tanja D., van de Loosdrecht, Arjan A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4612333/ https://www.ncbi.nlm.nih.gov/pubmed/26216454 http://dx.doi.org/10.1007/s00262-015-1741-1 |
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