Cargando…

DNA hypermethylation and decreased mRNA expression of MAL, PRIMA1, PTGDR and SFRP1 in colorectal adenoma and cancer

BACKGROUND: Colorectal cancer (CRC) development is accompanied by changes in expression for several genes; but the details of the underlying regulatory procesess remain unknown. Our aims were to assess the role of epigenetic processes in tumour formation and to identify characteristic DNA methylatio...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kalmár, Alexandra, Péterfia, Bálint, Hollósi, Péter, Galamb, Orsolya, Spisák, Sándor, Wichmann, Barnabás, Bodor, András, Tóth, Kinga, Patai, Árpád V., Valcz, Gábor, Nagy, Zsófia Brigitta, Kubák, Vivien, Tulassay, Zsolt, Kovalszky, Ilona, Molnár, Béla
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4612409/ https://www.ncbi.nlm.nih.gov/pubmed/26482433 http://dx.doi.org/10.1186/s12885-015-1687-x

Ejemplares similares

Myofibroblast-Derived SFRP1 as Potential Inhibitor of Colorectal Carcinoma Field Effect
por: Valcz, Gábor, et al.
Publicado: (2014)

Comprehensive DNA Methylation Analysis Reveals a Common Ten-Gene Methylation Signature in Colorectal Adenomas and Carcinomas
por: Patai, Árpád V., et al.
Publicado: (2015)

Gene promoter and exon DNA methylation changes in colon cancer development – mRNA expression and tumor mutation alterations
por: Molnár, Béla, et al.
Publicado: (2018)

Aging related methylation influences the gene expression of key control genes in colorectal cancer and adenoma
por: Galamb, Orsolya, et al.
Publicado: (2016)

Construction of a multiplex mutation hot spot PCR panel: the first step towards colorectal cancer genotyping on the GS Junior platform
por: Péterfia, Bálint, et al.
Publicado: (2017)

Promoter Hypermethylation-Related Reduced Somatostatin Production Promotes Uncontrolled Cell Proliferation in Colorectal Cancer
por: Leiszter, Katalin, et al.
Publicado: (2015)

Potential Biomarkers of Colorectal Adenoma–Dysplasia–Carcinoma Progression: mRNA Expression Profiling and In Situ Protein Detection on TMAs Reveal 15 Sequentially Upregulated and 2 Downregulated Genes
por: Galamb, Orsolya, et al.
Publicado: (2009)

Genome-Wide Screening of Genes Regulated by DNA Methylation in Colon Cancer Development
por: Spisák, Sándor, et al.
Publicado: (2012)

Sporadic Colorectal Cancer Development Shows Rejuvenescence Regarding Epithelial Proliferation and Apoptosis
por: Leiszter, Katalin, et al.
Publicado: (2013)

Genome-wide expression profiling in colorectal cancer focusing on lncRNAs in the adenoma-carcinoma transition
por: Kalmár, Alexandra, et al.
Publicado: (2019)

Colorectal adenoma and carcinoma specific miRNA profiles in biopsy and their expression in plasma specimens
por: Nagy, Zsófia Brigitta, et al.
Publicado: (2017)

Dysplasia-Carcinoma Transition Specific Transcripts in Colonic Biopsy Samples
por: Galamb, Orsolya, et al.
Publicado: (2012)

Applicability of Antibody and mRNA Expression Microarrays for Identifying Diagnostic and Progression Markers of Early and Late Stage Colorectal Cancer
por: Spisák, Sándor, et al.
Publicado: (2010)

Gene-expression analysis of a colorectal cancer-specific discriminatory transcript set on formalin-fixed, paraffin-embedded (FFPE) tissue samples
por: Kalmár, Alexandra, et al.
Publicado: (2015)

Detection of Methylated Septin 9 in Tissue and Plasma of Colorectal Patients with Neoplasia and the Relationship to the Amount of Circulating Cell-Free DNA
por: Tóth, Kinga, et al.
Publicado: (2014)

Global DNA hypomethylation of colorectal tumours detected in tissue and liquid biopsies may be related to decreased methyl-donor content
por: Szigeti, Krisztina A., et al.
Publicado: (2022)

Promoter Hypomethylation and Increased Expression of the Long Non-coding RNA LINC00152 Support Colorectal Carcinogenesis
por: Galamb, Orsolya, et al.
Publicado: (2020)

Reversal of gene expression changes in the colorectal normal-adenoma pathway by NS398 selective COX2 inhibitor
por: Galamb, O, et al.
Publicado: (2010)

Detection of Methylated SEPT9 in Plasma Is a Reliable Screening Method for Both Left- and Right-Sided Colon Cancers
por: Tóth, Kinga, et al.
Publicado: (2012)

Aberrant septin 9 DNA methylation in colorectal cancer is restricted to a single CpG island
por: Wasserkort, Reinhold, et al.
Publicado: (2013)

PTGDR gene expression and response to dexamethasone treatment in an in vitro model
por: Marcos-Vadillo, Elena, et al.
Publicado: (2017)

G Protein-Coupled Receptor Genes, PTGDR1, PTGDR2, and PTGIR, Are Candidate Epigenetic Biomarkers and Predictors for Treated Patients with HPV-Associated Oropharyngeal Cancer
por: Misawa, Kiyoshi, et al.
Publicado: (2020)

Controversials of Microscopic Colitis
por: Mihaly, Emese, et al.
Publicado: (2021)

In silico Identification of SFRP1 as a Hypermethylated Gene in Colorectal Cancers
por: Kim, Jongbum, et al.
Publicado: (2014)

Inflammation, Adenoma and Cancer: Objective Classification of Colon Biopsy Specimens with Gene Expression Signature
por: Galamb, Orsolya, et al.
Publicado: (2008)

Cell Free DNA of Tumor Origin Induces a ‘Metastatic’ Expression Profile in HT-29 Cancer Cell Line
por: Fűri, István, et al.
Publicado: (2015)

Diagnostic and prognostic potential of tissue and circulating long non-coding RNAs in colorectal tumors
por: Galamb, Orsolya, et al.
Publicado: (2019)

No Association of PTGDR −441C/T Polymorphism with Asthma in a North Indian Population
por: Birbian, Niti, et al.
Publicado: (2011)

PTGDR expression is upregulated through retinoic acid receptors (RAR) mechanism in allergy
por: García-Sánchez, Asunción, et al.
Publicado: (2019)

MAL hypermethylation is a tissue-specific event that correlates with MAL mRNA expression in esophageal carcinoma
por: Jin, Zhe, et al.
Publicado: (2013)

S-Adenosylmethionine Treatment of Colorectal Cancer Cell Lines Alters DNA Methylation, DNA Repair and Tumor Progression-Related Gene Expression
por: Zsigrai, Sára, et al.
Publicado: (2020)

Intestinal tumor suppression in Apc(Min/+) mice by prostaglandin D(2) receptor PTGDR
por: Tippin, Brigette L, et al.
Publicado: (2014)

PTGDR2 Expression in Peripheral Blood as a Potential Biomarker in Adult Patients with Asthma
por: García-Sánchez, Asunción, et al.
Publicado: (2021)

Complete Genes May Pass from Food to Human Blood
por: Spisák, Sándor, et al.
Publicado: (2013)

Peripheral Blood Based Discrimination of Ulcerative Colitis and Crohn’s Disease from Non-IBD Colitis by Genome-Wide Gene Expression Profiling
por: Sipos, Ferenc, et al.
Publicado: (2011)

Hypermethylated MAL gene – a silent marker of early colon tumorigenesis
por: Lind, Guro E, et al.
Publicado: (2008)

MAL promoter hypermethylation as a novel prognostic marker in gastric cancer
por: Buffart, T E, et al.
Publicado: (2008)

Syndecan-1 Promotes Hepatocyte-Like Differentiation of Hepatoma Cells Targeting Ets-1 and AP-1
por: Hollósi, Péter, et al.
Publicado: (2020)

Come prima meglio di prima : commedia in tre atti /
por: Pirandello, Luigi, 1867-1936
Publicado: (1929)

Association between SFRP promoter hypermethylation and different types of cancer: A systematic review and meta-analysis
por: Yu, Jun, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_1bl1frhsci4pbl8mj90iq4msb0