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The utility of transposon mutagenesis for cancer studies in the era of genome editing
The use of transposons as insertional mutagens to identify cancer genes in mice has generated a wealth of information over the past decade. Here, we discuss recent major advances in transposon-mediated insertional mutagenesis screens and compare this technology with other screening strategies.
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4612416/ https://www.ncbi.nlm.nih.gov/pubmed/26481584 http://dx.doi.org/10.1186/s13059-015-0794-y |