Cargando…

Relapsing pneumonitis due to two distinct inhibitors of the MAPK/ERK pathway: report of a case

BACKGROUND: BRAF and MEK are component of the MAPK/ERK pathway and inhibitors of these proteins have significantly improved the outcome of metastatic melanoma. We report for the first time two sequential episodes of pneumonitis presumably induced by trametinib (a MEK inhibitor) and vemurafenib (a BR...

Descripción completa

Detalles Bibliográficos
Autores principales:	Giraud, Violaine, Longvert, Christine, Houlle-Crepin, Solène, Danel, Claire, Labrune, Sylvie, Camus, Philippe, Saiag, Philippe, Chinet, Thierry
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Case Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4612419/ https://www.ncbi.nlm.nih.gov/pubmed/26481107 http://dx.doi.org/10.1186/s12885-015-1754-3

Ejemplares similares

Clinical factors associated with early progression and grade 3–4 toxicity in patients with advanced non-small-cell lung cancers treated with nivolumab
por: Dumenil, Coraline, et al.
Publicado: (2018)

Molecular characterization of circulating tumor cells in lung cancer: moving beyond enumeration
por: Wang, Lei, et al.
Publicado: (2017)

Feasibility of spirometry in primary care to screen for COPD: a pilot study
por: Giraud, Violaine, et al.
Publicado: (2016)

Positive plasma cotinine during platinum-based chemotherapy is associated with poor response rate in advanced non-small cell lung cancer patients
por: Dacosta-Noble, Philippine, et al.
Publicado: (2019)

Role of antibiotic use, plasma citrulline and blood microbiome in advanced non-small cell lung cancer patients treated with nivolumab
por: Ouaknine Krief, Julia, et al.
Publicado: (2019)

Sequential ctDNA whole-exome sequencing in advanced lung adenocarcinoma with initial durable tumor response on immune checkpoint inhibitor and late progression
por: Giroux Leprieur, Etienne, et al.
Publicado: (2020)

Relapsing nitrofurantoin-induced pneumonitis
por: Turner, Richard D., et al.
Publicado: (2011)

Impact du confinement lié au COVID-19 sur le retard au diagnostic et la sévérité du mélanome
por: Molinier, Rafaele, et al.
Publicado: (2021)

ERK1 and ERK2 MAPK are key regulators of distinct gene sets in zebrafish embryogenesis
por: Krens, SF Gabby, et al.
Publicado: (2008)

MAPK-ERK Pathway
por: Park, Jong-In
Publicado: (2023)

Efficacy of Large Use of Combined Hypofractionated Radiotherapy in a Cohort of Anti-PD-1 Monotherapy-Treated Melanoma Patients
por: Saiag, Philippe, et al.
Publicado: (2022)

MMP-13 In-Vivo Molecular Imaging Reveals Early Expression in Lung Adenocarcinoma
por: Salaün, Mathieu, et al.
Publicado: (2015)

ERK1/2/MAPK pathway-dependent regulation of the telomeric factor TRF2
por: Picco, Vincent, et al.
Publicado: (2016)

Efficacy of combined hypo-fractionated radiotherapy and anti-PD-1 monotherapy in difficult-to-treat advanced melanoma patients
por: Roger, Anissa, et al.
Publicado: (2018)

ERK/MAPK signalling pathway and tumorigenesis
por: Guo, Yan-Jun, et al.
Publicado: (2020)

The MAPK MEK1/2-ERK1/2 Pathway and Its Implication in Hepatocyte Cell Cycle Control
por: Guégan, Jean-Philippe, et al.
Publicado: (2012)

Distinct functions for ERKs?
por: Lloyd, Alison C
Publicado: (2006)

Regulation of ERK-MAPK signaling in human epidermis
por: Cursons, Joseph, et al.
Publicado: (2015)

MAPK/ERK Signaling in Regulation of Renal Differentiation
por: Kurtzeborn, Kristen, et al.
Publicado: (2019)

MAPK/ERK Signaling Pathway in Hepatocellular Carcinoma
por: Moon, Hyuk, et al.
Publicado: (2021)

Navigating the ERK1/2 MAPK Cascade
por: Martin-Vega, Ana, et al.
Publicado: (2023)

The MAPK/ERK-Signaling Pathway Regulates the Expression and Distribution of Tight Junction Proteins in the Mouse Proximal Epididymis
por: Kim, Bongki, et al.
Publicado: (2015)

Growth Development of French Children Born after In Vitro Maturation
por: Foix-L’Hélias, Laurence, et al.
Publicado: (2014)

Baseline Hedgehog Pathway Activation and Increase of Plasma Wnt1 Protein Are Associated with Resistance to Immune Checkpoint Inhibitors in Advanced Non-Small-Cell Lung Cancer
por: Mehlman, Camille, et al.
Publicado: (2021)

Regulation of SREBPs by Sphingomyelin in Adipocytes via a Caveolin and Ras-ERK-MAPK-CREB Signaling Pathway
por: Makdissy, Nehman, et al.
Publicado: (2015)

Activation of MAPK ERK in peripheral nerve after injury
por: Agthong, S, et al.
Publicado: (2006)

The ERK MAPK Pathway Is Essential for Skeletal Development and Homeostasis
por: Kim, Jung-Min, et al.
Publicado: (2019)

Human DNA Virus Exploitation of the MAPK-ERK Cascade
por: DuShane, Jeanne K., et al.
Publicado: (2019)

Multiple sclerosis is linked to MAPK(ERK) overactivity in microglia
por: ten Bosch, George J. A., et al.
Publicado: (2021)

Spatially Distinct Neutrophil Responses within the Inflammatory Lesions of Pneumonic Plague
por: Stasulli, Nikolas M., et al.
Publicado: (2015)

Knowledge Gaps and Research Priorities in Immune Checkpoint Inhibitor–related Pneumonitis. An Official American Thoracic Society Research Statement
por: Sears, Catherine R., et al.
Publicado: (2019)

Acute exacerbation of COPD during pulmonary rehabilitation: outcomes and risk prediction
por: Herer, Bertrand, et al.
Publicado: (2018)

Optogenetic actuator – ERK biosensor circuits identify MAPK network nodes that shape ERK dynamics
por: Dessauges, Coralie, et al.
Publicado: (2022)

Flecainide-induced pneumonitis: a case report
por: Moureau, Gauthier, et al.
Publicado: (2022)

Plasma Biomarkers Screening by Multiplex ELISA Assay in Patients with Advanced Non-Small Cell Lung Cancer Treated with Immune Checkpoint Inhibitors
por: Costantini, Adrien, et al.
Publicado: (2020)

Pneumonitis
por: Napier, L. Everard, et al.
Publicado: (1942)

Pneumonitis
Publicado: (1911)

Pneumonitis
Publicado: (1871)

Radiation Versus Immune Checkpoint Inhibitor Associated Pneumonitis: Distinct Radiologic Morphologies
por: Chen, Xuguang, et al.
Publicado: (2021)

The Respiratory Microbiome in Chronic Hypersensitivity Pneumonitis Is Distinct from That of Idiopathic Pulmonary Fibrosis
por: Invernizzi, Rachele, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_ghm1hvgobv0vctq2d1u3pcp381