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The kinase inhibitor D11 induces caspase-mediated cell death in cancer cells resistant to chemotherapeutic treatment

BACKGROUND: Multi-drug resistance and predisposition to metastasize are major clinical problems in cancer treatment. Malignant primary brain tumor and pancreatic cancer are two well-known examples of malignant tumors resistant to conventional therapies where aberrant EGFR-mediated and NF-κB signal t...

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Detalles Bibliográficos
Autores principales:	Guerra, Barbara, Fischer, Mette, Schaefer, Susanne, Issinger, Olaf-Georg
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4612421/ https://www.ncbi.nlm.nih.gov/pubmed/26480820 http://dx.doi.org/10.1186/s13046-015-0234-6

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