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Prevalence of β(S)-globin gene haplotypes, α-thalassemia (3.7 kb deletion) and redox status in patients with sickle cell anemia in the state of Paraná, Brazil
The aim of this study was to determine the frequency of beta S-globin gene (β(S) globin) haplotypes and alpha thalassemia with 3.7 kb deletion (−α(3.7kb) thalassemia) in the northwest region of Paraná state, and to investigate the oxidative and clinical-hematological profile of β(S) globin carriers...
Autores principales: | Shimauti, Eliana LitsukoTomimatsu, Silva, Danilo Grunig Humberto, de Souza, Eniuce Menezes, de Almeida, Eduardo Alves, Leal, Francismar Prestes, Bonini-Domingos, Claudia Regina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Sociedade Brasileira de Genética
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4612597/ https://www.ncbi.nlm.nih.gov/pubmed/26500435 http://dx.doi.org/10.1590/S1415-475738320140231 |
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