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Biosafety and Biosecurity: A Relative Risk-Based Framework for Safer, More Secure, and Sustainable Laboratory Capacity Building
BACKGROUND: Laboratory capacity building is characterized by a paradox between endemicity and resources: countries with high endemicity of pathogenic agents often have low and intermittent resources (water, electricity) and capacities (laboratories, trained staff, adequate regulations). Meanwhile, c...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4612646/ https://www.ncbi.nlm.nih.gov/pubmed/26539427 http://dx.doi.org/10.3389/fpubh.2015.00241 |
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author | Dickmann, Petra Sheeley, Heather Lightfoot, Nigel |
author_facet | Dickmann, Petra Sheeley, Heather Lightfoot, Nigel |
author_sort | Dickmann, Petra |
collection | PubMed |
description | BACKGROUND: Laboratory capacity building is characterized by a paradox between endemicity and resources: countries with high endemicity of pathogenic agents often have low and intermittent resources (water, electricity) and capacities (laboratories, trained staff, adequate regulations). Meanwhile, countries with low endemicity of pathogenic agents often have high-containment facilities with costly infrastructure and maintenance governed by regulations. The common practice of exporting high biocontainment facilities and standards is not sustainable and concerns about biosafety and biosecurity require careful consideration. METHODS: A group at Chatham House developed a draft conceptual framework for safer, more secure, and sustainable laboratory capacity building. RESULTS: The draft generic framework is guided by the phrase “LOCAL – PEOPLE – MAKE SENSE” that represents three major principles: capacity building according to local needs (local) with an emphasis on relationship and trust building (people) and continuous outcome and impact measurement (make sense). CONCLUSION: This draft generic framework can serve as a blueprint for international policy decision-making on improving biosafety and biosecurity in laboratory capacity building, but requires more testing and detailing development. |
format | Online Article Text |
id | pubmed-4612646 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-46126462015-11-04 Biosafety and Biosecurity: A Relative Risk-Based Framework for Safer, More Secure, and Sustainable Laboratory Capacity Building Dickmann, Petra Sheeley, Heather Lightfoot, Nigel Front Public Health Public Health BACKGROUND: Laboratory capacity building is characterized by a paradox between endemicity and resources: countries with high endemicity of pathogenic agents often have low and intermittent resources (water, electricity) and capacities (laboratories, trained staff, adequate regulations). Meanwhile, countries with low endemicity of pathogenic agents often have high-containment facilities with costly infrastructure and maintenance governed by regulations. The common practice of exporting high biocontainment facilities and standards is not sustainable and concerns about biosafety and biosecurity require careful consideration. METHODS: A group at Chatham House developed a draft conceptual framework for safer, more secure, and sustainable laboratory capacity building. RESULTS: The draft generic framework is guided by the phrase “LOCAL – PEOPLE – MAKE SENSE” that represents three major principles: capacity building according to local needs (local) with an emphasis on relationship and trust building (people) and continuous outcome and impact measurement (make sense). CONCLUSION: This draft generic framework can serve as a blueprint for international policy decision-making on improving biosafety and biosecurity in laboratory capacity building, but requires more testing and detailing development. Frontiers Media S.A. 2015-10-21 /pmc/articles/PMC4612646/ /pubmed/26539427 http://dx.doi.org/10.3389/fpubh.2015.00241 Text en Copyright © 2015 Dickmann, Sheeley and Lightfoot. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Public Health Dickmann, Petra Sheeley, Heather Lightfoot, Nigel Biosafety and Biosecurity: A Relative Risk-Based Framework for Safer, More Secure, and Sustainable Laboratory Capacity Building |
title | Biosafety and Biosecurity: A Relative Risk-Based Framework for Safer, More Secure, and Sustainable Laboratory Capacity Building |
title_full | Biosafety and Biosecurity: A Relative Risk-Based Framework for Safer, More Secure, and Sustainable Laboratory Capacity Building |
title_fullStr | Biosafety and Biosecurity: A Relative Risk-Based Framework for Safer, More Secure, and Sustainable Laboratory Capacity Building |
title_full_unstemmed | Biosafety and Biosecurity: A Relative Risk-Based Framework for Safer, More Secure, and Sustainable Laboratory Capacity Building |
title_short | Biosafety and Biosecurity: A Relative Risk-Based Framework for Safer, More Secure, and Sustainable Laboratory Capacity Building |
title_sort | biosafety and biosecurity: a relative risk-based framework for safer, more secure, and sustainable laboratory capacity building |
topic | Public Health |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4612646/ https://www.ncbi.nlm.nih.gov/pubmed/26539427 http://dx.doi.org/10.3389/fpubh.2015.00241 |
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