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TAp73 transcriptionally represses BNIP3 expression
TAp73 is a tumor suppressor transcriptional factor, belonging to p53 family. Alteration of TAp73 in tumors might lead to reduced DNA damage response, cell cycle arrest and apoptosis. Carcinogen-induced TAp73(−/−) tumors display also increased angiogenesis, associated to hyperactivition of hypoxia in...
Autores principales: | Petrova, Varvara, Mancini, Mara, Agostini, Massimiliano, Knight, Richard A, Annicchiarico-Petruzzelli, Margherita, Barlev, Nikolai A, Melino, Gerry, Amelio, Ivano |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4612661/ https://www.ncbi.nlm.nih.gov/pubmed/25950386 http://dx.doi.org/10.1080/15384101.2015.1044178 |
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