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Inactivation of the budding yeast cohesin loader Scc2 alters gene expression both globally and in response to a single DNA double strand break

Genome integrity is fundamental for cell survival and cell cycle progression. Important mechanisms for keeping the genome intact are proper sister chromatid segregation, correct gene regulation and efficient repair of damaged DNA. Cohesin and its DNA loader, the Scc2/4 complex have been implicated i...

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Detalles Bibliográficos
Autores principales:	Lindgren, Emma, Hägg, Sara, Giordano, Fosco, Björkegren, Johan, Ström, Lena
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2014
Materias:	Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4612677/ https://www.ncbi.nlm.nih.gov/pubmed/25483075 http://dx.doi.org/10.4161/15384101.2014.964108

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