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Interaction of Cx43 with Hsc70 regulates G1/S transition through CDK inhibitor p27

Connexin 43 (Cx43) functions as a cell growth suppressor. We have demonstrated that Cx43 interacts with heat shock cognate protein 70 (Hsc70) for regulating cell proliferation. Hsc70 interacts with CDK inhibitor p27, which regulates the assembly and subcellular localization of cyclin D1-CDK4-p27 com...

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Detalles Bibliográficos
Autores principales: Hino, Hitoshi, Dai, Ping, Yoshida, Tatsushi, Hatakeyama, Tomoya, Harada, Yoshinori, Otsuji, Eigo, Okuda, Tsukasa, Takamatsu, Tetsuro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4612729/
https://www.ncbi.nlm.nih.gov/pubmed/26481195
http://dx.doi.org/10.1038/srep15365