Cargando…

Interaction of Cx43 with Hsc70 regulates G1/S transition through CDK inhibitor p27

Connexin 43 (Cx43) functions as a cell growth suppressor. We have demonstrated that Cx43 interacts with heat shock cognate protein 70 (Hsc70) for regulating cell proliferation. Hsc70 interacts with CDK inhibitor p27, which regulates the assembly and subcellular localization of cyclin D1-CDK4-p27 com...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hino, Hitoshi, Dai, Ping, Yoshida, Tatsushi, Hatakeyama, Tomoya, Harada, Yoshinori, Otsuji, Eigo, Okuda, Tsukasa, Takamatsu, Tetsuro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4612729/ https://www.ncbi.nlm.nih.gov/pubmed/26481195 http://dx.doi.org/10.1038/srep15365

Ejemplares similares

Connexin43 Functions as a Novel Interacting Partner of Heat Shock Cognate Protein 70
por: Hatakeyama, Tomoya, et al.
Publicado: (2013)

5-Aminolevulinic Acid-Induced Protoporphyrin IX Fluorescence Imaging for Tumor Detection: Recent Advances and Challenges
por: Harada, Yoshinori, et al.
Publicado: (2022)

Combining TGF-β signal inhibition and connexin43 silencing for iPSC induction from mouse cardiomyocytes
por: Dai, Ping, et al.
Publicado: (2014)

TGF-β Signaling Regulates Pancreatic β-Cell Proliferation through Control of Cell Cycle Regulator p27 Expression
por: Suzuki, Tomoyuki, et al.
Publicado: (2013)

Hsc70’s trip to the tip
por: Leslie, Mitch
Publicado: (2015)

Structure of clathrin coat with bound Hsc70 and auxilin: mechanism of Hsc70-facilitated disassembly
por: Xing, Yi, et al.
Publicado: (2010)

Comparative analysis of the anticoagulant activities and immunogenicity of HSC70 and HSC70(TKD) of Haemaphysalis flava
por: Liu, Yu-Ke, et al.
Publicado: (2022)

Simplified and optimized multispectral imaging for 5-ALA-based fluorescence diagnosis of malignant lesions
por: Minamikawa, Takeo, et al.
Publicado: (2016)

Hsc70 Focus Formation at the Periphery of HSV-1 Transcription Sites Requires ICP27
por: Li, Ling, et al.
Publicado: (2008)

5-ALA-assistant automated detection of lymph node metastasis in gastric cancer patients
por: Matsumoto, Tatsuya, et al.
Publicado: (2020)

Accumulation of Uroporphyrin I in Necrotic Tissues of Squamous Cell Carcinoma after Administration of 5-Aminolevulinic Acid
por: Beika, Masatomo, et al.
Publicado: (2021)

Hsc70 is required for endocytosis and clathrin function in Drosophila
por: Chang, Henry C., et al.
Publicado: (2002)

Mechanism and Complex Roles of HSC70 in Viral Infections
por: Wang, Zeng, et al.
Publicado: (2020)

Exploration of the cysteine reactivity of human inducible Hsp70 and cognate Hsc70
por: Hong, Zhouping, et al.
Publicado: (2022)

Chronic Stress and Gonadectomy Affect the Expression of Cx37, Cx40 and Cx43 in the Spinal Cord
por: Jurić, Marija, et al.
Publicado: (2021)

Comparative Analysis of Cx31 and Cx43 in Differentiation-Competent Rodent Keratinocytes
por: Au, Akina, et al.
Publicado: (2020)

Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells
por: Ryu, Seung W., et al.
Publicado: (2020)

A novel role of Cx43-composed GJIC in PDT phototoxicity: an implication of Cx43 for the enhancement of PDT efficacy
por: Wu, Deng-Pan, et al.
Publicado: (2019)

Correlations of Differentially Expressed Gap Junction Connexins Cx26, Cx30, Cx32, Cx43 and Cx46 with Breast Cancer Progression and Prognosis
por: Teleki, Ivett, et al.
Publicado: (2014)

Electrophysiology of Single and Aggregate Cx43 Hemichannels
por: Brokamp, Cole, et al.
Publicado: (2012)

Importance of Cx43 for Right Ventricular Function
por: Boengler, Kerstin, et al.
Publicado: (2021)

The Interplay of Cx26, Cx32, Cx37, Cx40, Cx43, Cx45, and Panx1 in Inner-Ear Development of Yotari (dab1−/−) Mice and Humans
por: Lesko, Josip, et al.
Publicado: (2022)

Cardiac remodeling and arrhythmogenesis are ameliorated by administration of Cx43 mimetic peptide Gap27 in heart failure rats
por: Lucero, Claudia M., et al.
Publicado: (2020)

Deep-UV excitation fluorescence microscopy for detection of lymph node metastasis using deep neural network
por: Matsumoto, Tatsuya, et al.
Publicado: (2019)

Biochemical and Proteomic Analysis of Ubiquitination of Hsc70 and Hsp70 by the E3 Ligase CHIP
por: Soss, Sarah E., et al.
Publicado: (2015)

Connexin 43 mimetic peptide Gap27 reveals potential differences in the role of Cx43 in wound repair between diabetic and non-diabetic cells
por: Pollok, Simone, et al.
Publicado: (2011)

The Connexin Mimetic Peptide Gap27 and Cx43-Knockdown Reveal Differential Roles for Connexin43 in Wound Closure Events in Skin Model Systems
por: Faniku, Chrysovalantou, et al.
Publicado: (2018)

Opposite Effects of Moderate and Extreme Cx43 Deficiency in Conditional Cx43-Deficient Mice on Angiotensin II-Induced Cardiac Fibrosis
por: Valls-Lacalle, Laura, et al.
Publicado: (2019)

Hsp70 Architecture: The Formation of Novel Polymeric Structures of Hsp70.1 and Hsc70 after Proteotoxic Stress
por: Steel, Rohan, et al.
Publicado: (2012)

Detection of Lymph Node Metastases in Human Colorectal Cancer by Using 5-Aminolevulinic Acid-Induced Protoporphyrin IX Fluorescence with Spectral Unmixing
por: Harada, Kenichi, et al.
Publicado: (2013)

Similarities and Differences of Hsp70, hsc70, Grp78 and Mortalin as Cancer Biomarkers and Drug Targets
por: Rai, Rajani, et al.
Publicado: (2021)

Insights from the protein sequence and structure analysis of PgHsc70 and OsHsp70 genes
por: Baloji, Gugulothu, et al.
Publicado: (2022)

Alteration of Cx37, Cx40, Cx43, Cx45, Panx1, and Renin Expression Patterns in Postnatal Kidneys of Dab1-/- (yotari) Mice
por: Lozić, Mirela, et al.
Publicado: (2021)

Cardiac Cx43, Cx40 and Cx45 co-assembling: involvement of connexins epitopes in formation of hemichannels and Gap junction channels
por: Desplantez, Thomas
Publicado: (2017)

Altered Expression of Glial Gap Junction Proteins Cx43, Cx30, and Cx47 in the 5XFAD Model of Alzheimer’s Disease
por: Angeli, Stella, et al.
Publicado: (2020)

Expression of hsp 27, hsp 60, hsc 70, and hsp 70 stress response genes in cultured human urothelial cells (UROtsa) exposed to lethal and sublethal concentrations of sodium arsenite.
por: Rossi, Michael R, et al.
Publicado: (2002)

Hsc70 chaperone activity is required for the cytosolic slow axonal transport of synapsin
por: Ganguly, Archan, et al.
Publicado: (2017)

Hsc70/Stub1 promotes the removal of individual oxidatively stressed peroxisomes
por: Chen, Bo-Hua, et al.
Publicado: (2020)

Selective Binding of HSC70 and its Co-Chaperones to Structural Hotspots on CFTR
por: Baaklini, Imad, et al.
Publicado: (2020)

Clinical Implications of HSC70 Expression in Clear Cell Renal Cell Carcinoma
por: Zhang, Yixiao, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_34tt09340193plkvmjfdsvn05p