HMGB1 Contributes to the Expression of P-Glycoprotein in Mouse Epileptic Brain through Toll-Like Receptor 4 and Receptor for Advanced Glycation End Products

The objective of the present study was to investigate the role of high-mobility group box-1 (HMGB1) in the seizure-induced P-glycoprotein (P-gp) overexpression and the underlying mechanism. Kainic acid (KA)-induced mouse seizure model was used for in vivo experiments. Male C57BL/6 mice were divided...

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Detalles Bibliográficos
Autores principales: Chen, Yan, Huang, Xian-Jing, Yu, Nian, Xie, Yuan, Zhang, Kang, Wen, Fang, Liu, Hao, Di, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4613137/
https://www.ncbi.nlm.nih.gov/pubmed/26485677
http://dx.doi.org/10.1371/journal.pone.0140918

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4613137/
https://www.ncbi.nlm.nih.gov/pubmed/26485677
http://dx.doi.org/10.1371/journal.pone.0140918

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