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Cisplatin Targeting of Bacterial Ribosomal RNA Hairpins

Cisplatin is a clinically important chemotherapeutic agent known to target purine bases in nucleic acids. In addition to major deoxyribonucleic acid (DNA) intrastrand cross-links, cisplatin also forms stable adducts with many types of ribonucleic acid (RNA) including siRNA, spliceosomal RNAs, tRNA,...

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Detalles Bibliográficos
Autores principales: Dedduwa-Mudalige, Gayani N. P., Chow, Christine S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4613259/
https://www.ncbi.nlm.nih.gov/pubmed/26370969
http://dx.doi.org/10.3390/ijms160921392