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Cisplatin Targeting of Bacterial Ribosomal RNA Hairpins
Cisplatin is a clinically important chemotherapeutic agent known to target purine bases in nucleic acids. In addition to major deoxyribonucleic acid (DNA) intrastrand cross-links, cisplatin also forms stable adducts with many types of ribonucleic acid (RNA) including siRNA, spliceosomal RNAs, tRNA,...
Autores principales: | Dedduwa-Mudalige, Gayani N. P., Chow, Christine S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4613259/ https://www.ncbi.nlm.nih.gov/pubmed/26370969 http://dx.doi.org/10.3390/ijms160921392 |
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