Cargando…

Ghrelin Attenuates Liver Fibrosis through Regulation of TGF-β1 Expression and Autophagy

Ghrelin is a stomach-derived growth hormone secretagogue that promotes various physiological effects, including energy metabolism and amelioration of inflammation. The purpose of this study was to investigate the protective mechanism of ghrelin against liver fibrosis. Liver fibrosis was induced in C...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mao, Yuqing, Zhang, Shaoren, Yu, Fujun, Li, Huanqing, Guo, Chuanyong, Fan, Xiaoming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4613288/ https://www.ncbi.nlm.nih.gov/pubmed/26378522 http://dx.doi.org/10.3390/ijms160921911

Ejemplares similares

Inhibition of ghrelin o-acyltransferase attenuated lipotoxicity by inducing autophagy via AMPK–mTOR pathway
por: Zhang, Shaoren, et al.
Publicado: (2018)

Ghrelin reduces liver impairment in a model of concanavalin A-induced acute hepatitis in mice
por: Mao, Yuqing, et al.
Publicado: (2015)

Autophagy: a new target for nonalcoholic fatty liver disease therapy
por: Mao, Yuqing, et al.
Publicado: (2016)

Bergenin Attenuates Hepatic Fibrosis by Regulating Autophagy Mediated by the PPAR-γ/TGF-β Pathway
por: Xia, Yujing, et al.
Publicado: (2020)

Protective Effect of Astaxanthin on Liver Fibrosis through Modulation of TGF-β1 Expression and Autophagy
por: Shen, Miao, et al.
Publicado: (2014)

Protective effect of fucoidan from Fucus vesiculosus on liver fibrosis via the TGF-β1/Smad pathway-mediated inhibition of extracellular matrix and autophagy
por: Li, Jingjing, et al.
Publicado: (2016)

Ghrelin Inhibits Intestinal Epithelial Cell Apoptosis Through the Unfolded Protein Response Pathway in Ulcerative Colitis
por: Zhang, Lin, et al.
Publicado: (2021)

TGF‐β/Smad and JAK/STAT pathways are involved in the anti‐fibrotic effects of propylene glycol alginate sodium sulphate on hepatic fibrosis
por: Xu, Shizan, et al.
Publicado: (2020)

Apigenin Alleviates Liver Fibrosis by Inhibiting Hepatic Stellate Cell Activation and Autophagy via TGF-β1/Smad3 and p38/PPARα Pathways
por: Ji, Jie, et al.
Publicado: (2021)

Aspirin attenuates liver fibrosis by suppressing TGF-β1/Smad signaling
por: Sun, Yimin, et al.
Publicado: (2022)

PPARγ/NF‐κB and TGF‐β1/Smad pathway are involved in the anti‐fibrotic effects of levo‐tetrahydropalmatine on liver fibrosis
por: Yu, Qiang, et al.
Publicado: (2021)

ENMD-1068 inhibits liver fibrosis through attenuation of TGF-β1/Smad2/3 signaling in mice
por: Sun, Quan, et al.
Publicado: (2017)

Quercetin prevents hepatic fibrosis by inhibiting hepatic stellate cell activation and reducing autophagy via the TGF-β1/Smads and PI3K/Akt pathways
por: Wu, Liwei, et al.
Publicado: (2017)

Tyrosine kinase receptor B attenuates liver fibrosis by inhibiting TGF-β/SMAD signaling
por: Song, Yu, et al.
Publicado: (2023)

Sulfatase-2 Regulates Liver Fibrosis through the TGF-β Signaling Pathway
por: Nakamura, Ikuo, et al.
Publicado: (2021)

(Pro)renin Receptor Knockdown Attenuates Liver Fibrosis Through Inactivation of ERK/TGF-β1/SMAD3 Pathway
por: Hsieh, Yun-Cheng, et al.
Publicado: (2021)

Author Correction: ENMD-1068 inhibits liver fibrosis through attenuation of TGF-β1/Smad2/3 signaling in mice
por: Sun, Quan, et al.
Publicado: (2019)

Del-1, an Endogenous Inhibitor of TGF-β Activation, Attenuates Fibrosis
por: Kim, Dong-Young, et al.
Publicado: (2020)

Lin28a attenuates TGF-β-induced renal fibrosis
por: Jung, Gwon-Soo, et al.
Publicado: (2020)

Ferulic acid attenuates liver fibrosis and hepatic stellate cell activation via inhibition of TGF-β/Smad signaling pathway
por: Mu, Mao, et al.
Publicado: (2018)

Salvianolic Acid B Attenuates Experimental Pulmonary Fibrosis through Inhibition of the TGF-β Signaling Pathway
por: Liu, Qingmei, et al.
Publicado: (2016)

Surfactant protein D attenuates sub-epithelial fibrosis in allergic airways disease through TGF-β
por: Ogawa, Hirohisa, et al.
Publicado: (2014)

TGFβ promotes fibrosis by MYST1-dependent epigenetic regulation of autophagy
por: Zehender, Ariella, et al.
Publicado: (2021)

Casticin attenuates liver fibrosis and hepatic stellate cell activation by blocking TGF-β/Smad signaling pathway
por: Zhou, Ling, et al.
Publicado: (2017)

Pemafibrate Pretreatment Attenuates Apoptosis and Autophagy during Hepatic Ischemia-Reperfusion Injury by Modulating JAK2/STAT3β/PPARα Pathway
por: Cheng, Ziqi, et al.
Publicado: (2021)

Ferulic acid attenuates liver fibrosis and hepatic stellate cell activation via inhibition of TGF-β/Smad signaling pathway [Corrigendum]
por: Mu, Mao, et al.
Publicado: (2019)

Attenuation of CCl(4)-Induced Hepatic Fibrosis in Mice by Vaccinating against TGF-β1
por: Fan, Xiaobao, et al.
Publicado: (2013)

Pioglitazone Protects Tubular Epithelial Cells during Kidney Fibrosis by Attenuating miRNA Dysregulation and Autophagy Dysfunction Induced by TGF-β
por: Manzéger, Anna, et al.
Publicado: (2023)

Acupuncture attenuates renal interstitial fibrosis via the TGF-β/Smad pathway
por: Zuo, Zheng, et al.
Publicado: (2019)

Syndecan-4 Inhibits the Development of Pulmonary Fibrosis by Attenuating TGF-β Signaling
por: Tanino, Yoshinori, et al.
Publicado: (2019)

Pien-Tze-Huang alleviates CCl(4)-induced liver fibrosis through the inhibition of HSC autophagy and the TGF-β1/Smad2 pathway
por: Zhang, Yuqin, et al.
Publicado: (2022)

Ghrelin Inhibits Post-Operative Adhesions via Blockage of the TGF-β Signaling Pathway
por: Bianchi, Enrica, et al.
Publicado: (2016)

Dual Delivery of TGF-β3 and Ghrelin in Microsphere/Hydrogel Systems for Cartilage Regeneration
por: Lin, Jianjing, et al.
Publicado: (2021)

MicroRNA-130a attenuates cardiac fibrosis after myocardial infarction through TGF-β/Smad signaling by directly targeting TGF-β receptor 1
por: Feng, Yu, et al.
Publicado: (2022)

Deregulation of selective autophagy during aging and pulmonary fibrosis: the role of TGFβ1
por: Sosulski, Meredith L, et al.
Publicado: (2015)

Enhancer of Zeste Homologue 2 Inhibition Attenuates TGF-β Dependent Hepatic Stellate Cell Activation and Liver Fibrosis
por: Martin-Mateos, Rosa, et al.
Publicado: (2018)

Autophagy as a Therapeutic Target for Chronic Kidney Disease and the Roles of TGF-β1 in Autophagy and Kidney Fibrosis
por: Ruby, Miss, et al.
Publicado: (2023)

Fluorofenidone alleviates liver fibrosis by inhibiting hepatic stellate cell autophagy via the TGF-β1/Smad pathway: implications for liver cancer
por: Peng, Xiongqun, et al.
Publicado: (2023)

Lumican promotes joint fibrosis through TGF‐β signaling
por: Xiao, Dahai, et al.
Publicado: (2020)

Isorhamnetin Inhibits Liver Fibrosis by Reducing Autophagy and Inhibiting Extracellular Matrix Formation via the TGF-β1/Smad3 and TGF-β1/p38 MAPK Pathways
por: Liu, Ning, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_e3jva1ntr8j1a9c1e70mmj8j3k