Enantioselective Pharmacokinetics of α-Lipoic Acid in Rats

α-Lipoic acid (LA) is widely used for nutritional supplements as a racemic mixture, even though the R enantiomer is biologically active. After oral administration of the racemic mixture (R-α-lipoic acid (RLA) and S-α-lipoic acid (SLA) mixed at the ratio of 50:50) to rats, RLA showed higher plasma co...

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Detalles Bibliográficos
Autores principales: Uchida, Ryota, Okamoto, Hinako, Ikuta, Naoko, Terao, Keiji, Hirota, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4613335/
https://www.ncbi.nlm.nih.gov/pubmed/26402669
http://dx.doi.org/10.3390/ijms160922781

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4613335/
https://www.ncbi.nlm.nih.gov/pubmed/26402669
http://dx.doi.org/10.3390/ijms160922781

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