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Enantioselective Pharmacokinetics of α-Lipoic Acid in Rats
α-Lipoic acid (LA) is widely used for nutritional supplements as a racemic mixture, even though the R enantiomer is biologically active. After oral administration of the racemic mixture (R-α-lipoic acid (RLA) and S-α-lipoic acid (SLA) mixed at the ratio of 50:50) to rats, RLA showed higher plasma co...
Autores principales: | Uchida, Ryota, Okamoto, Hinako, Ikuta, Naoko, Terao, Keiji, Hirota, Takashi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4613335/ https://www.ncbi.nlm.nih.gov/pubmed/26402669 http://dx.doi.org/10.3390/ijms160922781 |
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