The Role of PTP1B O-GlcNAcylation in Hepatic Insulin Resistance

Protein tyrosine phosphatase 1B (PTP1B), which can directly dephosphorylate both the insulin receptor and insulin receptor substrate 1 (IRS-1), thereby terminating insulin signaling, reportedly plays an important role in insulin resistance. Accumulating evidence has demonstrated that O-GlcNAc modifi...

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Detalles Bibliográficos
Autores principales: Zhao, Yun, Tang, Zhuqi, Shen, Aiguo, Tao, Tao, Wan, Chunhua, Zhu, Xiaohui, Huang, Jieru, Zhang, Wanlu, Xia, Nana, Wang, Suxin, Cui, Shiwei, Zhang, Dongmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4613339/
https://www.ncbi.nlm.nih.gov/pubmed/26402673
http://dx.doi.org/10.3390/ijms160922856

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4613339/
https://www.ncbi.nlm.nih.gov/pubmed/26402673
http://dx.doi.org/10.3390/ijms160922856

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