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High variability of genomic instability and gene expression profiling in different HeLa clones

The HeLa cell line is one of the most popular cell lines in biomedical research, despite its well-known chromosomal instability. We compared the genomic and transcriptomic profiles of 4 different HeLa batches and showed that the gain and loss of genomic material varies widely between batches, drasti...

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Detalles Bibliográficos
Autores principales:	Frattini, Annalisa, Fabbri, Marco, Valli, Roberto, De Paoli, Elena, Montalbano, Giuseppe, Gribaldo, Laura, Pasquali, Francesco, Maserati, Emanuela
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4613361/ https://www.ncbi.nlm.nih.gov/pubmed/26483214 http://dx.doi.org/10.1038/srep15377

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