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Providing a molecular mechanism for P-glycoprotein; why would I bother?
It is almost 40 years since the drug efflux pump P-glycoprotein (permeability glycoprotein or P-gp) was shown to confer multi-drug resistance in cancer cells. This protein has been one of the most extensively investigated transport proteins due to its intriguing mechanism and its affect in oncology....
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Portland Press Ltd.
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4613492/ https://www.ncbi.nlm.nih.gov/pubmed/26517914 http://dx.doi.org/10.1042/BST20150131 |