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Efficient entry of cell-penetrating peptide nona-arginine into adherent cells involves a transient increase in intracellular calcium
Understanding the mechanism of entry of cationic peptides such as nona-arginine (R(9)) into cells remains an important challenge to their use as efficient drug-delivery vehicles. At nanomolar to low micromolar R(9) concentrations and at physiological temperature, peptide entry involves endocytosis....
Autores principales: | Melikov, Kamran, Hara, Ann, Yamoah, Kwabena, Zaitseva, Elena, Zaitsev, Eugene, Chernomordik, Leonid V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4613506/ https://www.ncbi.nlm.nih.gov/pubmed/26272944 http://dx.doi.org/10.1042/BJ20150272 |
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