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Tristetraprolin regulation of interleukin-22 production
Interleukin (IL)-22 is a STAT3-activating cytokine displaying characteristic AU-rich elements (ARE) in the 3′-untranslated region (3′-UTR) of its mRNA. This architecture suggests gene regulation by modulation of mRNA stability. Since related cytokines undergo post-transcriptional regulation by ARE-b...
Autores principales: | Härdle, Lorena, Bachmann, Malte, Bollmann, Franziska, Pautz, Andrea, Schmid, Tobias, Eberhardt, Wolfgang, Kleinert, Hartmut, Pfeilschifter, Josef, Mühl, Heiko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4613560/ https://www.ncbi.nlm.nih.gov/pubmed/26486958 http://dx.doi.org/10.1038/srep15112 |
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