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The oncogene EVI1 enhances transcriptional and biological responses of human myeloid cells to all-trans retinoic acid
The product of the ecotropic virus integration site 1 (EVI1) gene, whose overexpression is associated with a poor prognosis in myeloid leukemias and some epithelial tumors, regulates gene transcription both through direct DNA binding and through modulation of the activity of other sequence specific...
Autores principales: | Steinmetz, Birgit, Hackl, Hubert, Slabáková, Eva, Schwarzinger, Ilse, Smějová, Monika, Spittler, Andreas, Arbesu, Itziar, Shehata, Medhat, Souček, Karel, Wieser, Rotraud |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4613657/ https://www.ncbi.nlm.nih.gov/pubmed/25486480 http://dx.doi.org/10.4161/15384101.2014.946869 |
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